| Type | Description |
|---|---|
| Definition | NME/NM23 nucleoside diphosphate kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity. | 33086728 |
| 2019-11-30 10:15:00 | Study in transgenic mice reports that the increased levels of Ang-2 are indeed crucial for the development of retinal damage under NDPK-B deficiency and provides evidence that the enhanced O-GlcNAcylation of FoxO1 after NDPK-B depletion is regulating its protein expression and thereby driving the upregulation of Ang-2 in endothelial cells. | 30002415 |
| 2019-07-13 11:39:00 | Data identify NME2 as one of the two NME isoforms involved in class switch recombination (CSR) in B cells. Its knockdown results in decreased CSR. On the contrary of Nme1; NME2 binds to S regions only after stimulation. | 30411342 |
| 2018-01-13 14:25:00 | Results demonstrate that nm23 plays a vital role in decidualization in mice and humans and that nm23 gene expression is hormonally regulated. | 27604954 |
| 2016-12-17 11:31:00 | NDPKB-deficient mice are a suitable model for studying mechanisms underlying diabetic retinal vascular damage. | 25900369 |
| Type | IDs |
|---|---|
| Synonymous | NM23-H2, NM23B, nm23-M2 |
| Gene |
UniProtKB-ID:
NDKB_MOUSE,
Q5NC82_MOUSE
UniprotKB:
Q01768,
Q5NC82
UniParc:
UPI0000003EFD
EMBL:
AK150419,
BC086893,
BC066995,
BC086892,
AK012447,
AK169120,
AK151262,
X68193
Ensembl:
ENSMUSG00000020857
KO:
mmu:18103
|
| Nucleutide sequences |
EMBL-CDS:
AAH86893.1,
AAH66995.1,
AAH86892.1,
CAA48275.1,
BAB28246.1,
BAE29543.1,
BAE30250.1,
BAE40900.1
Ensembl_TRS:
ENSMUST00000021217,
ENSMUST00000072566
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000021217,
ENSMUSP00000103476
RefSeq:
NP_001070997.1,
NP_032731.1
|
| Others |
UniRef100:
UniRef100_Q01768
UniRef90:
UniRef90_Q01768
UniRef50:
UniRef50_Q01768
UniGene:
Mm.1260
CCDS:
CCDS25246.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员