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18102 Nme1

18102

Nme1

NME/NM23 nucleoside diphosphate kinase 1

protein-coding

Mus musculus

基因描述

Type Description
Definition NME/NM23 nucleoside diphosphate kinase 1

研究结论

Date Results Publications
2020-05-09 12:51:00 these data indicate metastasis suppressor activity of NME1 in melanoma is mediated by induction of ITGB3 gene transcription. 30458180
2019-07-13 11:39:00 Data identify NME1 as one of the two NME isoforms involved in class switch recombination (CSR) in B cells. Its knockdown leads to increased CSR. On the contrary of NME2, NME1 binds to S regions prior to stimulation. 30411342
2017-09-09 11:07:00 Deletion of NME1 reduced total NDPK activity and exacerbated activation of the stress-related MAPK, JNK, in the liver in response to paraquat. NDPK activity protects cells from acute oxidative stress by inhibiting activation of JNK in mammal models. 28077425
2015-08-15 11:27:00 EMMPRIN ensures proper actomyosin-driven maturation of competent endothelial junctions by forming a molecular complex with gamma-catenin (also known as junction plakoglobin) and Nm23 (also known as NME1), a nucleoside diphosphate kinase 24994937
2013-04-06 10:50:00 data suggested that NME1 acts as a switcher or reprogramming factor which involves in oligodentrocyte versus neuron cell fate specification in vitro 23023023

名称对应

Type IDs
Synonymous AL024257, NDPK-A, NM23-M1, NM23A
Gene
UniProtKB-ID: NDKA_MOUSE, Q5NC81_MOUSE
UniprotKB: P15532, Q5NC81
UniParc: UPI000000188F
EMBL: M35970, U85511, AK136353, AF033377, M65037, BC005629, AK034899
Ensembl: ENSMUSG00000037601
KO: mmu:18102
Nucleutide sequences
EMBL-CDS: AAH05629.1, AAB42080.1, AAA63391.1, AAB87689.1, AAA39826.1, BAE22943.1, BAC28873.1
Ensembl_TRS: ENSMUST00000135884
Protein sequencees
Ensembl_PRO: ENSMUSP00000117022
RefSeq: NP_001365783.1, NP_032730.1, XP_036012304.1, XP_036012303.1
Others
UniRef100: UniRef100_P15532
UniRef90: UniRef90_P15532
UniRef50: UniRef50_P15532
UniGene: Mm.439702
CCDS: CCDS25247.1

全选

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