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18101 Nmbr

18101

Nmbr

neuromedin B receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition neuromedin B receptor

研究结论

Date Results Publications
2020-07-18 12:38:00 Data show genetically disruption of NB-R in mice ASC or pharmacological antagonism of NB-R in 3T3-L1 cells impairs adipogenesis. 31067509
2020-02-08 10:48:00 NMB-treated mice were less susceptible to virus challenge, as evidenced by increased survival, increased body weight, and decreased viral NP expression compared with the control animals. As expected, opposing effects were observed in the NMBR antagonist-treated cells and mice, which further confirmed the effects of NMB. 31601264
2017-12-09 11:54:00 Neuromedin B expression identifies retrotrapezoid nucleus neurons in the mouse. 29066557
2017-10-21 12:24:00 NMB or NMBR silencing inhibited M-CSF/c-Fms-mediated downstream signaling pathways like activation of ERK and Akt and induction of D-type cyclins, cyclin D1 and D2. 28780306
2017-03-18 10:53:00 mice with deletion of NB receptor have lower insulinemia, especially in response to oral glucose, and females also exhibited a better glucose tolerance, suggesting the involvement of neuromedin b and its receptor in regulation of insulin secretion induced by incretins, and also, in insulin sensitivity. 27756093

名称对应

Type IDs
Synonymous BB182387
Gene
UniProtKB-ID: NMBR_MOUSE, Q0VEH1_MOUSE
UniprotKB: O54799, Q0VEH1
UniParc: UPI0000021767
EMBL: BC119237, AB010281
Ensembl: ENSMUSG00000019865
KO: mmu:18101
Nucleutide sequences
EMBL-CDS: BAA24405.1, AAI19238.1
Ensembl_TRS: ENSMUST00000020015
Protein sequencees
Ensembl_PRO: ENSMUSP00000020015
RefSeq: NP_032729.1, XP_030100801.1
Others
UniRef100: UniRef100_O54799
UniRef90: UniRef90_P24053
UniRef50: UniRef50_P28336
UniGene: Mm.487342
CCDS: CCDS23707.1

全选

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研究热度

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