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181 AGRP

181

AGRP

agouti related neuropeptide

protein-coding

Homo sapiens

基因描述

Type Description
Definition agouti related neuropeptide

研究结论

Date Results Publications
2021-02-13 13:21:00 Mitochondrial Dynamics and Microglia as New Targets in Metabolism Regulation. 32414136
2020-06-06 10:08:00 The plasma AgRP levels were higher in those with active acromegaly than in the matched healthy subjects, and decreased after treatment with pegvisomant or with surgery. 31361303
2019-12-21 12:25:00 Plasma agouti-related protein (AgRP) level is elevated in Cushing disease, tightly correlates with cortisol concentration, and decline with surgical cure. These data support the regulation of AgRP by glucocorticoids in humans. 30597030
2019-02-02 12:05:00 AgRP acted as a biased agonist in MC3R, decreasing cAMP activity of constitutively active mutant (F347A) MC3R but stimulating ERK1/2 activation in both wild type and F347A MC3Rs. 27208795
2018-01-13 11:17:00 AgRP is not associated with changes in hunger or satiety, and can change without corresponding changes in leptin. This suggests that AgRP may not be involved in the episodic control of appetite and the release of AgRP may involve signals other than leptin. 27476955

名称对应

Type IDs
Synonymous AGRT, ART, ASIP2
Gene
UniProtKB-ID: AGRP_HUMAN, C6SUN5_HUMAN
UniprotKB: O00253, C6SUN5
UniParc: UPI0000046BA7
EMBL: AF281309, BK006637, CH471092, BC110443, U88063, U89485, DQ374394, AF314194
Ensembl: ENSG00000159723
KO: hsa:181
Nucleutide sequences
EMBL-CDS: AAK96256.1, ABC88473.1, AAB68621.1, AAB52240.1, AAL09457.1, AAI10444.1, EAW83137.1, DAA06531.1
Gene_ORFName: hCG_28814
Ensembl_TRS: ENST00000290953
Protein sequencees
Ensembl_PRO: ENSP00000290953
RefSeq: NP_001129.1
Others
UniRef100: UniRef100_O00253
UniRef90: UniRef90_O00253
UniRef50: UniRef50_O00253
UniGene: Hs.104633
CCDS: CCDS10839.1

全选

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研究热度

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