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18099 Nlk

18099

Nlk

nemo like kinase

protein-coding

Mus musculus

基因描述

Type Description
Definition nemo like kinase

研究结论

Date Results Publications
2020-08-29 12:49:00 Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase. 32620751
2019-03-16 12:57:00 The phosphatase activity of WIP1 increases Wnt activity through Nemo-like kinase (NLK). WIP1 directly interacted with NLK, which is highly homologous to p38 MAPK, a WIP1 substrate, and dephosphorylated its activation site. 28185954
2017-08-19 11:36:00 our data suggest that NLK/Nemo acts as an endogenous regulator of Hippo signaling by controlling nuclear localization and activity of YAP/Yorkie. 27979972
2017-04-08 12:02:00 NLK is a novel signaling molecule for proper lung development through the interconnection between epithelial and endothelial cells during lung morphogenesis 27035511
2016-07-02 11:44:00 NLK can phosphorylate the mutant polyglutamine-expanded androgen receptor protein, enhance its aggregation, and promote androgen receptor-dependent gene transcription by regulating androgen receptor-cofactor interactions. 26308581

名称对应

Type IDs
Synonymous AI194375
Gene
UniProtKB-ID: NLK_MOUSE, Q3TV73_MOUSE
UniprotKB: O54949, Q3TV73
UniParc: UPI0000507715, UPI00005AD3D2
EMBL: BC057667, AL591177, BC058652, AK160340, AF036332, AL591376
Ensembl: ENSMUSG00000017376
KO: mmu:18099
Nucleutide sequences
EMBL-CDS: AAH58652.2, AAC24499.1, AAH57667.2, BAE35746.1
Ensembl_TRS: ENSMUST00000142739
Protein sequencees
Ensembl_PRO: ENSMUSP00000119345
RefSeq: XP_036012300.1, XP_036012302.1, NP_032728.3, XP_036012301.1
Others
UniRef100: UniRef100_A0A556TRQ3, UniRef100_O54949
UniRef90: UniRef90_A0A556TRQ3, UniRef90_Q9UBE8
UniRef50: UniRef50_Q9UBE8, UniRef50_A0A556TRQ3
UniGene: Mm.9001
CCDS: CCDS25113.2

全选

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