| Type | Description |
|---|---|
| Definition | NK6 homeobox 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:38:00 | Obesity-induced reduced expression of the lncRNA ROIT impairs insulin transcription by downregulation of Nkx6.1 methylation. | 32008054 |
| 2018-06-09 10:27:00 | our data reveal a novel mechanism of Notch1 transcriptional regulation in the ventral spinal cord by Nkx6.1 via its binding with Notch1 enhancer CR2 during embryonic development. | 27924849 |
| 2015-06-20 13:06:00 | Nkx6.1 plays a vital role in astrocyte specification and differentiation in the ventral spinal cord. | 25285789 |
| 2014-07-12 12:55:00 | MAFA, MAFB, NKX6.1, and PDX1 activity provides a gauge of islet beta cell function, with loss of MAFA (and/or MAFB) representing an early indicator of beta cell inactivity | 23863625 |
| 2014-06-28 13:23:00 | Over time, Nkx6.1-deficient beta cells acquired molecular characteristics of delta cells, revealing a molecular link between impaired beta cell functional properties and loss of cell identity. | 24035389 |
| Type | IDs |
|---|---|
| Synonymous | NKX6A, Nkx6.1 |
| Gene |
UniProtKB-ID:
NKX61_MOUSE
UniprotKB:
Q99MA9
UniParc:
UPI0000027DFB
EMBL:
AF291666,
BC138019,
BC138020,
AF357883
Ensembl:
ENSMUSG00000035187
KO:
mmu:18096
|
| Nucleutide sequences |
EMBL-CDS:
AAI38020.1,
AAG30415.1,
AAI38021.1,
AAK37567.1
Ensembl_TRS:
ENSMUST00000044125
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000042716
RefSeq:
NP_659204.1
|
| Others |
UniRef100:
UniRef100_Q99MA9
UniRef90:
UniRef90_Q99MA9
UniRef50:
UniRef50_Q99MA9
UniGene:
Mm.193072
CCDS:
CCDS19471.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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