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18095 Nkx3-1

18095

Nkx3-1

NK3 homeobox 1

protein-coding

Mus musculus

基因描述

Type Description
Definition NK3 homeobox 1

研究结论

Date Results Publications
2021-02-06 13:59:00 CRISPR/Cas9-Mediated Point Mutation in Nkx3.1 Prolongs Protein Half-Life and Reverses Effects Nkx3.1 Allelic Loss. 32943441
2020-06-20 11:25:00 The prostate cancer suppressors PTEN and NKX3.1 interact and loss of PTEN is responsible, at least in part, for progressive loss of NKX3.1 that occurs during tumor progression. 31213464
2019-06-22 15:03:00 loss of function of NKX3.1 accelerates inflammation-driven prostate cancer initiation potentially via aberrant cellular plasticity and impairment of cellular differentiation. 30266798
2019-04-20 11:59:00 NKX3-1 substitutes for exogenous OCT4 to reprogram both mouse and human fibroblasts at comparable efficiencies and generate fully pluripotent stem cells. 30013107
2018-05-26 10:14:00 Prostate cancer patients with low NKX3.1 expression are optimal candidates for intervention with 5alpha-reductase inhibitors as an adjunct to active surveillance. 28385453

名称对应

Type IDs
Synonymous Bax, NKX3.1, NKX3A, Nkx-3.1, bagpipe
Gene
UniProtKB-ID: NKX31_MOUSE, Q3UVH8_MOUSE
UniprotKB: P97436, Q3UVH8
UniParc: UPI0000021DD5
EMBL: U88542, BC132427, AK137281, U73460, BC132401
Ensembl: ENSMUSG00000022061
KO: mmu:18095
Nucleutide sequences
EMBL-CDS: AAC52956.1, AAB58025.1, BAE23291.1, AAI32402.1, AAI32428.1
Ensembl_TRS: ENSMUST00000022646
Protein sequencees
Ensembl_PRO: ENSMUSP00000022646
RefSeq: NP_035051.1
Others
UniRef100: UniRef100_P97436
UniRef90: UniRef90_P97436
UniRef50: UniRef50_P97436
UniGene: Mm.3520
CCDS: CCDS27237.1

全选

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研究热度

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