| Type | Description |
|---|---|
| Definition | NK2 homeobox 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:58:00 | Conjugated activation of myocardial-specific transcription of Gja5 by a pair of Nkx2-5-Shox2 co-responsive elements. | 32687896 |
| 2020-11-28 13:17:00 | Nkx2-5 defines distinct scaffold and recruitment phases during formation of the murine cardiac Purkinje fiber network. | 33082351 |
| 2020-07-11 12:30:00 | Nkx2-5 defines a population of pacemaker cells in the transitional zone. Despite Nkx2-5 being dispensable for Sinoatrial node morphogenesis during embryogenesis, its deletion hampers atrial activation by the pacemaker. | 31320323 |
| 2019-12-21 10:17:00 | Analysis of murine hearts and human induced pluripotent stem cell-derived cardiomyocytes provided histologic and molecular evidence for the NKX2-5 variant's contribution as a genetic modifier. | 31147515 |
| 2019-12-14 11:29:00 | Study shows that Nkx2-5 directly represses cardiac Furin expression. Furthermore, Furin is required for the maturation of the cardiac progenitor cells and for the correct formation of the atrioventricular junction where it is expressed. Finally, study shows that this function is, at least in part, mediated by modulation of the BMP pathway. | 30840660 |
| Type | IDs |
|---|---|
| Synonymous | Csx, Nkx-2.5, Nkx2.5, tinman |
| Gene |
UniProtKB-ID:
NKX25_MOUSE,
Q3UQU2_MOUSE
UniprotKB:
P42582,
Q3UQU2
UniParc:
UPI00000213F4
EMBL:
L20300,
BC139299,
AF091351,
AK142146,
BC139303,
X75415
Ensembl:
ENSMUSG00000015579
KO:
mmu:18091
|
| Nucleutide sequences |
EMBL-CDS:
AAC97934.1,
CAA53169.1,
BAE24947.1,
AAI39300.1,
AAI39304.1
Ensembl_TRS:
ENSMUST00000015723
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000015723
RefSeq:
XP_006523860.1,
NP_032726.1
|
| Others |
UniRef100:
UniRef100_P42582
UniRef90:
UniRef90_P42582
UniRef50:
UniRef50_P42582
UniGene:
Mm.41974
CCDS:
CCDS28556.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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