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180894 lite-1

180894

lite-1

High-energy light unresponsive protein 1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition High-energy light unresponsive protein 1

研究结论

Date Results Publications
2021-01-23 13:04:00 Regulation of photosensation by hydrogen peroxide and antioxidants in C. elegans. 33301443
2017-04-08 10:58:00 Unlike typical photoreceptors employing a prosthetic chromophore to capture photons, LITE-1 strictly depends on its protein conformation for photon absorption; further two tryptophan residues critical for LITE-1 function were identified. Interestingly, unlike GPCRs, LITE-1 adopts a reversed membrane topology. Thus, LITE-1, a taste receptor homolog, represents a distinct type of photoreceptor in the animal kingdom. 27863243
2015-04-18 10:15:00 receptor family members LITE-1 and GUR-3 are required for the inhibition of feeding by light and hydrogen peroxide. 25640076
2010-06-28 11:58:00 data suggest a model in which LITE-1 transduces light signals in a photoreceptor neuron via G protein signaling, leading to upregulation of the second messenger cGMP, followed by opening of cGMP-sensitive CNG channels and stimulation of photoreceptors 20436480

名称对应

Type IDs
Gene
UniProtKB-ID: LITE1_CAEEL
UniprotKB: Q17990
UniParc: UPI000007EAE5
EMBL: BX284606, AF387605
EnsemblGenome: WBGene00001803
KO: cel:CELE_C14F11.3
Nucleutide sequences
EMBL-CDS: AAK70488.1, CCD64541.1
Gene_ORFName: C14F11.3
EnsemblGenome_TRS: C14F11.3.1
Protein sequencees
EnsemblGenome_PRO: C14F11.3.1
RefSeq: NP_509043.3
Others
UniRef100: UniRef100_Q17990
UniRef90: UniRef90_Q17990
UniRef50: UniRef50_Q17990
UniGene: Cel.802

全选

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研究热度

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