| Type | Description |
|---|---|
| Definition | dihydropyrimidinase like 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | Pivotal role of DPYSL2A in KLF4-mediated monocytic differentiation of acute myeloid leukemia cells. | 33219287 |
| 2020-09-19 16:22:00 | Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) promotes the aggressiveness of human uveal melanoma through dephosphorylation of CRMP2. | 30816227 |
| 2020-07-04 11:13:00 | Results revealed an array of multiple carbonylation sites in the functional motifs of CRMP2, particularly D-hook (for dimerization) and T-site (for tetramerization), which are critical for the activity of the CRMP2 tetramer. Carbonylated CRMP2 was stacked in the multimer conformation by irreversible cross-linking, resulting in loss of its function to bundle microtubules. | 31591136 |
| 2020-04-25 12:57:00 | CRMP2 SUMOylation exists widely in GBM cells and drives glioblastoma proliferation. Blocking CRMP2 SUMOylation through SUMOylation-incompetent mutant or small peptide suppresses CRMP2-induced GBM cell proliferation. | 31267313 |
| 2019-09-28 12:46:00 | The interaction between Prx2 and CRMP2 is conserved among humans and rodents. | 30315937 |
| Type | IDs |
|---|---|
| Synonymous | CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 |
| Gene |
UniProtKB-ID:
DPYL2_HUMAN,
Q59GB4_HUMAN,
A0A1C7CYX9_HUMAN
UniprotKB:
Q16555,
Q59GB4,
A0A1C7CYX9
UniParc:
UPI00004F6BE2,
UPI00017A7A1F,
UPI0000129864,
UPI0000416B71
EMBL:
AK291287,
U97105,
CH471080,
AC015564,
AB209195,
BC056408,
U17279,
AK299077,
AC015743,
D78013,
BC067109,
AB020777
Ensembl:
ENSG00000092964
KO:
hsa:1808
|
| Nucleutide sequences |
EMBL-CDS:
AAC05793.1,
BAG61143.1,
BAF83976.1,
AAA93202.1,
EAW63574.1,
EAW63573.1,
AAH67109.1,
BAA11191.1,
BAA86991.1,
AAH56408.1,
BAD92432.1
Ensembl_TRS:
ENST00000311151,
ENST00000523027,
ENST00000521913
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000431117,
ENSP00000309539,
ENSP00000427985
RefSeq:
NP_001231533.1,
NP_001184222.1,
NP_001377.1
|
| Others |
UniRef100:
UniRef100_A0A1C7CYX9,
UniRef100_Q16555
UniRef90:
UniRef90_A0A1C7CYX9,
UniRef90_Q16555
UniRef50:
UniRef50_O14531,
UniRef50_Q16555
UniGene:
Hs.593187
CCDS:
CCDS59096.1,
CCDS6051.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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