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180679 lin-18

180679

lin-18

Inactive tyrosine-protein kinase RYK

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Inactive tyrosine-protein kinase RYK

研究结论

Date Results Publications
2015-08-08 11:16:00 Ryk-intracellular domain fragment suppressed neuroprotection by lin-18/Ryk loss-of-function in expanded-polyQ nematodes, repressed FOXO transcriptional activity, and abolished beta-catenin protection of mutant htt striatal cells against cell death 24960609
2015-05-16 10:56:00 Release of LIN-18ICD by cleavage at the membrane is not the main mechanism of LIN-18 signaling in vulval cells. results suggest LIN-18 intracellular domain interacts with Wnt pathway and a 14-3-3 protein and likely plays a minor role in LIN-18 signaling 24975394
2014-03-22 11:09:00 In a Frizzled-dependent manner, PLR-1 reduces surface levels of the Wnt receptors CAM-1/Ror and LIN-18/Ryk. 24401370
2012-01-28 11:36:00 ceMIB (Caenorhabditis elegans Mindbomb/Y47D3A.22) plays a role in the regulation of C. elegans Wnt/RYK (lin-18) /TCF signaling. 21875946
2010-01-21 00:00:00 lin-17 (Frizzled type Wnt receptor) and lin-18 (Ryk) regulate the pattern of POP-1 localization and cell type specification in the posterior half of the vulva. 15649465

名称对应

Type IDs
Gene
UniProtKB-ID: RYK_CAEEL
UniprotKB: G5EGT9
UniParc: UPI000007768E
EMBL: BX284606, AF133217
EnsemblGenome: WBGene00003007
KO: cel:CELE_C16B8.1
Nucleutide sequences
EMBL-CDS: AAD24877.1, CCD64652.1
Gene_ORFName: C16B8.1
EnsemblGenome_TRS: C16B8.1.1, C16B8.1.2
Protein sequencees
EnsemblGenome_PRO: C16B8.1.2, C16B8.1.1
RefSeq: NP_508684.4
Others
UniRef100: UniRef100_G5EGT9
UniRef90: UniRef90_G5EGT9
UniRef50: UniRef50_G5EGT9
UniGene: Cel.19586

全选

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研究热度

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