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180622 ddr-2

180622

ddr-2

Discoidin domain-containing receptor tyrosine kinase B

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Discoidin domain-containing receptor tyrosine kinase B

研究结论

Date Results Publications
2020-02-15 10:53:00 Overexpression of svh-2, but not of ddr-2, can suppress the axon regeneration defect observed in svh-11 mutants, suggesting that SVH-11 functions between DDR-2 and SVH-2 in this glycosylation pathway. Furthermore, we found that DDR-2 is N-glycosylated at the Asn-141 residue located in its discoidin domain, and mutation of this residue caused an axon regeneration defect. 31371405
2017-05-13 21:39:00 the scaffold protein SHC-1 interacts with both DDR-2 and SVH-2. Furthermore, we demonstrate that overexpression of svh-2 and shc-1 suppresses the delay in axon regeneration observed in ddr-2 mutants, suggesting that DDR-2 functions upstream of SVH-2 and SHC-1 27984580
2013-03-16 11:05:00 Discoidin domain receptors guide axons along longitudinal tracts in C. elegans 23147028

名称对应

Type IDs
Gene
UniProtKB-ID: DDRB_CAEEL
UniprotKB: Q95ZV7
UniParc: UPI000007DA1E, UPI0000075F16
EMBL: BX284606
EnsemblGenome: WBGene00017381
KO: cel:CELE_F11D5.3
Nucleutide sequences
EMBL-CDS: CCD69234.1, CCD69233.1
Gene_ORFName: F11D5.3
EnsemblGenome_TRS: F11D5.3b.2, F11D5.3a.1, F11D5.3b.1
Protein sequencees
EnsemblGenome_PRO: F11D5.3b.2, F11D5.3b.1, F11D5.3a.1
RefSeq: NP_508572.1, NP_508573.1
Others
UniRef100: UniRef100_Q95ZV7
UniRef90: UniRef90_Q95ZV7
UniRef50: UniRef50_Q95ZV7
UniGene: Cel.17220

全选

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研究热度

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