| Type | Description |
|---|---|
| Definition | Presenilin sel-12 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 10:34:00 | Mutations in the C. elegans gene encoding a PSEN homolog, sel-12 result in mitochondrial metabolic defects that promote neurodegeneration as a result of oxidative stress. | 29989545 |
| 2016-09-17 10:12:00 | mutations in sel-12 result in defects in calcium homeostasis, leading to mitochondrial dysfunction | 26500256 |
| 2010-01-21 00:00:00 | Data report the cloning and characterization of spr-3 and spr-4, which encode large basic zinc-finger proteins which act as transcriptional repressors for sel-12 [spr-3 and spr-4]. | 12668626 |
| 2010-01-21 00:00:00 | A genetic null allele mutant, sel-12(ar171), showed resistance to oxidative stress and prevented mitochondrial dysfunction-induced apoptosis. | 12556527 |
| 2010-01-21 00:00:00 | spr-2 mutations do not suppress sel-12 by affecting nonsense mediated decay, and increase the levels of sel-12 transcripts with premature translation termination codons. | 19302704 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PSN_CAEEL
UniprotKB:
P52166
UniParc:
UPI00001327DF
EMBL:
AF171064,
BX284606,
U35660
EnsemblGenome:
WBGene00004769
KO:
cel:CELE_F35H12.3
|
| Nucleutide sequences |
EMBL-CDS:
AAD50991.1,
AAA85511.1,
CCD70617.1
Gene_ORFName:
F35H12.3
EnsemblGenome_TRS:
F35H12.3.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F35H12.3.1
RefSeq:
NP_508175.1
|
| Others |
UniRef100:
UniRef100_P52166
UniRef90:
UniRef90_P52166
UniRef50:
UniRef50_P52166
UniGene:
Cel.19557
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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