| Type | Description |
|---|---|
| Definition | nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:06:00 | REGgamma regulates NFkappaB activity by specifically degrading IkBepsilon to regulate inflammation in testicular Leydig cells. | 30816488 |
| 2017-05-20 10:50:00 | The basic residues Lys-717 and Lys-719 in the C-terminal region of ANK7 contribute to IkappaBzeta binding to the Lcn2 promoter, probably via interaction with the cytosine-rich element required for Lcn2 activation; glutamate substitution for both lysines results in a loss of transcriptionally active complex formation without affecting direct contact of IkappaBzeta with p50. | 27489104 |
| 2012-02-18 11:07:00 | The data imply that regulation of these c-Rel-dependent lymphoid responses is a non-redundant function of IkappaBepsilon. | 21915344 |
| 2010-01-21 00:00:00 | Neither IkappaBalpha nor IkappaBepsilon deficiency had major effects on natural killer cell generation while their combined absence led to NF-kappaB hyperactivation. | 14764534 |
| 2010-01-21 00:00:00 | IkappaBepsilon deficiency in mice leads to neonatal death, elevated kappaB binding activity, overexpression of NF-kappaB target genes, and disruption of lymphocyte production. | 14665694 |
| Type | IDs |
|---|---|
| Synonymous | I-kappa-B-epsilon, IKBE, IkB-E, NF-kappa-BIE, ikB-epsilon |
| Gene |
UniProtKB-ID:
IKBE_MOUSE,
A0A3B2WAY2_MOUSE
UniprotKB:
O54910,
A0A3B2WAY2
UniParc:
UPI0000001A82,
UPI00001692F1
EMBL:
AK151450,
AC163677,
AF030896,
AK011965,
BC030923,
AK008843,
AK153248
Ensembl:
ENSMUSG00000023947
KO:
mmu:18037
|
| Nucleutide sequences |
EMBL-CDS:
BAB27943.1,
BAE31839.1,
AAH30923.1,
BAE30410.1,
BAB25924.1,
AAB97517.1
Ensembl_TRS:
ENSMUST00000024742,
ENSMUST00000233929
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024742,
ENSMUSP00000156580
RefSeq:
NP_001291885.1,
NP_032716.2
|
| Others |
UniRef100:
UniRef100_A0A3B2WAY2,
UniRef100_O54910
UniRef90:
UniRef90_O54910,
UniRef90_A0A3B2WAY2
UniRef50:
UniRef50_O54910
UniGene:
Mm.57043
CCDS:
CCDS28811.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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