| Type | Description |
|---|---|
| Definition | nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:27:00 | CpG-ODN-mediated TLR9 innate immune signalling and calcium dyshomeostasis converge on the NFkappaB inhibitory protein IkappaBbeta to drive IL1alpha and IL1beta expression. | 32064589 |
| 2016-03-05 11:42:00 | IkappaBbeta has essential functions within the Rel-NFkappaB generation module, specifically for the RelA:RelA homodimer, which controls a subset of NFkappaB target genes. | 25946967 |
| 2016-01-02 10:56:00 | these results mechanistically link the innate immune response mediated by IkappaBbeta/NF-kappaB to ET-1 expression and potentially reveal therapeutic targets for patients with Gram-negative septic shock. | 26342031 |
| 2014-09-20 10:40:00 | Dengue virus protease interacts with both IkappaBalpha and IkappaBbeta cleaving them in a mouse hemorrhage model. | 24973451 |
| 2014-04-26 11:02:00 | sustained NF-kappaB activity mediated by IkappaBbeta protects against hyperoxic lung injury through increased expression of antiapoptotic genes | 24066808 |
| Type | IDs |
|---|---|
| Synonymous | I(Kappa)B(beta), I-kappa-B-beta, IKB-beta, IKappaBbeta, IkB, IkBb, NF-kappa-BIB, ikB-B |
| Gene |
UniProtKB-ID:
IKBB_MOUSE
UniprotKB:
Q60778
UniParc:
UPI000000400F
EMBL:
U19799,
AK156731,
CH466593,
AK010218,
AK038631
Ensembl:
ENSMUSG00000030595
KO:
mmu:18036
|
| Nucleutide sequences |
EMBL-CDS:
BAE33825.1,
BAC30071.1,
EDL24118.1,
EDL24117.1,
BAB26774.1,
AAC52166.1
Ensembl_TRS:
ENSMUST00000032815,
ENSMUST00000085851
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000083012,
ENSMUSP00000032815
RefSeq:
NP_035038.2,
NP_001293151.1
|
| Others |
UniRef100:
UniRef100_Q60778
UniRef90:
UniRef90_Q60778
UniRef50:
UniRef50_Q15653
UniGene:
Mm.220333
CCDS:
CCDS21054.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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