| Type | Description |
|---|---|
| Definition | Defective pharyngeal development protein 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-13 12:38:00 | Reduced signaling through the insulin-like receptor daf-2/InsR in the maternal soma causes constitutively large progeny, and its effector daf-16/FoxO is required for this effect. nhr-49/Hnf4, pha-4/FoxA, and skn-1/Nrf also regulate progeny-size plasticity. Genetic analysis suggests that insulin-like signaling controls progeny size in part through regulation of nhr-49/Hnf4, and that pha-4/FoxA and skn-1/Nrf function | 27783623 |
| 2015-07-25 11:13:00 | results suggest that PHA-4 employs feed-forward loops to fine-tune gene expression and instil robustness in the system during energy crisis. | 25504288 |
| 2015-07-25 10:58:00 | these results suggest that Pol II recruitment, in addition to chromatin opening, is an important feature of PHA-4 pioneer factor activity. | 26089518 |
| 2015-06-20 10:25:00 | A network analysis of aging-associated miRNAs connected to transcription factors PHA-4/FOXA and SKN-1/Nrf revealed extensive regulatory interactions between PHA-4, SKN-1, and miRNAs undergoing dietary restriction. | 25242029 |
| 2013-08-31 10:16:00 | Suppression of misfolding in muscle cells is achieved not only by enhanced expression of HSP90 in muscle cells but also by elevated expression of HSP90 (Daf-21) in intestine or neuronal cells. This cell-nonautonomous control of HSP90 expression relies upon transcriptional feedback between somatic tissues that is regulated by the FoxA transcription factor PHA-4. | 23746847 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PHA4_CAEEL
UniprotKB:
Q17381
UniParc:
UPI0000D722CC,
UPI0000D722CB,
UPI0000083388
EMBL:
BX284605,
U51163
EnsemblGenome:
WBGene00004013
KO:
cel:CELE_F38A6.1
|
| Nucleutide sequences |
EMBL-CDS:
CAK12560.1,
AAA96319.1,
CAK12559.1,
CAB07378.1
Gene_ORFName:
F38A6.1
EnsemblGenome_TRS:
F38A6.1c.1,
F38A6.1a.1,
F38A6.1b.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F38A6.1a.1,
F38A6.1c.1,
F38A6.1b.1
RefSeq:
NP_001041116.1,
NP_001041115.1,
NP_001041114.1
|
| Others |
UniRef100:
UniRef100_Q17381
UniRef90:
UniRef90_Q17381
UniRef50:
UniRef50_Q17381
UniGene:
Cel.17389
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Huntsman Cancer Institute |
5 |
| 2 |
Yale University |
3 |
| 3 |
Harvard University |
2 |
| 4 |
The Salk Institute for Biological Studies |
1 |
| 5 |
University of Pennsylvania |
1 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Susan E Mango |
9 |
| 2 |
Dustin L Updike |
4 |
| 3 |
David E Hill |
2 |
| 4 |
Mark Gerstein |
2 |
| 5 |
S E Mango |
2 |