Type | Description |
---|---|
Definition | Serine/threonine-protein kinase unc-51 |
Date | Results | Publications |
---|---|---|
2019-07-13 12:05:00 | Using pharmacological and genetic approaches, we found that worms deficient for autophagy were short-lived during starvation and recovered poorly from extended starvation, indicating sensitivity to nutrient stress. Autophagy mutants unc-51/Atg1 and atg-18/Atg18 maintained greater mtDNA content than wild-type worms during starvation, suggesting that autophagy promotes mitochondrial degradation during starvation | 30133321 |
2010-06-14 11:18:00 | PP2A cooperates with UNC-51 to regulate axon guidance by regulating phosphorylation. | 20392746 |
2010-01-21 00:00:00 | Inactivation of unc-51, bec-1 and lgg-1, the worm counterparts of the yeast autophagy genes Atg1, Atg6 and Atg8 respectively, partially suppresses degeneration of neurons with toxic ion channel variants. | 17327275 |
2010-01-21 00:00:00 | Mutants with impaired growth cone functions, such as unc-51, often exhibit abnormal terminations and inappropriate trajectories at the distal ends of the M2 axons. | 12885562 |
2010-01-21 00:00:00 | VAB-8 and UNC-14 are substrates that mediate the function of UNC-51 in axon outgrowth | 15539493 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
UNC51_CAEEL
UniprotKB:
Q23023
UniParc:
UPI0000137C51
EMBL:
Z38016,
BX284605
EnsemblGenome:
WBGene00006786
KO:
cel:CELE_Y60A3A.1
|
Nucleutide sequences |
EMBL-CDS:
CAA86114.1,
CAB60406.1
Gene_ORFName:
Y60A3A.1
EnsemblGenome_TRS:
Y60A3A.1.1
|
Protein sequencees |
EnsemblGenome_PRO:
Y60A3A.1.1
RefSeq:
NP_507869.1
|
Others |
UniRef100:
UniRef100_Q23023
UniRef90:
UniRef90_Q23023
UniRef50:
UniRef50_Q23023
UniGene:
Cel.5550
|
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