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180185 par-4

180185

par-4

Serine/threonine-protein kinase par-4

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Serine/threonine-protein kinase par-4

研究结论

Date Results Publications
2018-12-22 11:22:00 the regulation of the cytoskeleton and cell polarity may contribute significantly to the tumour suppressor function of LKB1/par-4. 29907081
2017-06-03 11:27:00 our results imply that DAF-18/PTEN, through PAR-4/LKB1, can activate AAK-1/AMPK in the absence of apparent energy stress. As all components are conserved, similar signalling cascades may regulate stem cell activities in other organisms and be widely implicated in cancer. 28410423
2017-05-27 10:16:00 We report here that din-1S is required in parallel to par-4/LKB1 signaling within the gonad to establish cell cycle quiescence during the onset of the dauer stage. 27260305
2015-12-26 11:58:00 PAR-4/LKB1 impinges on myosin via two pathways, an anillin-dependent pathway that also responds to the cullin CUL-5 and an anillin-independent pathway involving the kinase PIG-1/MELK. 26416962
2014-09-27 12:05:00 DNA replication is asymmetrically regulated in the two-cell stage embryo and the PAR-4 and PAR-1 polarity proteins dampen DNA replication dynamics specifically in the posterior blastomere. 24841566

名称对应

Type IDs
Gene
Nucleutide sequences
Protein sequencees
RefSeq: NP_001367284.1, NP_001367285.1, NP_001366977.1
Others
UniGene: Cel.19519

全选

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研究热度

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