| Type | Description |
|---|---|
| Definition | NIMA (never in mitosis gene a)-related expressed kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-11-26 01:38:00 | NEK1 phosphorylates PP1gamma, leading to the dephosphorylation of WAPL, which, in turn, results in its retention on chromosome cores to promote loss of cohesion at the end of prophase I in mammals. | 27760328 |
| 2017-11-04 12:46:00 | Reduction in ADD1 protein in NEK1 mutant mice is associated with hyperphosphorylation of ADD1, thereby preventing the interaction with MYO10 during meiotic spindle formation | 28982183 |
| 2015-07-25 11:15:00 | Nek1 is detectable in all murine tissues but its expression in wild type and kat2J heterozygous kidneys decrease as the kidneys mature. In the embryonic kidney, Nek1 expression is most prominent in cells that will become podocytes and proximal tubules. | 25030234 |
| 2011-09-03 11:11:00 | results demonstrate that Nek1 is important for proper checkpoint control and characterize for the first time a DNA damage response that does not directly involve one of the known upstream mediator kinases, ATM or ATR | 21301226 |
| 2011-07-02 11:23:00 | data suggest that TAZ and Nek1 constitute a negative feedback loop linked through phosphorylation and ubiquitination and that the interaction of Nek1 and TAZ maintain polycystin 2 at the level needed for proper ciliogenesis | 21474562 |
| Type | IDs |
|---|---|
| Synonymous | D8Ertd790e, kat |
| Gene |
UniProtKB-ID:
NEK1_MOUSE,
B2RXQ4_MOUSE,
B7ZWK0_MOUSE,
B2RXX0_MOUSE,
Q3UXI0_MOUSE
UniprotKB:
P51954,
B2RXQ4,
B7ZWK0,
B2RXX0,
Q3UXI0
UniParc:
UPI0001747B62,
UPI000051268C,
UPI0001747B14,
UPI00005ABBA9,
UPI00001F5EA4
EMBL:
AY850065,
BC157939,
AC134339,
AC159302,
AK135564,
BC172091,
BC158009
Ensembl:
ENSMUSG00000031644
KO:
mmu:18004
|
| Nucleutide sequences |
EMBL-CDS:
AAB23529.2,
AAI57940.1,
AAI72091.1,
AAI58010.1,
BAE22583.1
Ensembl_TRS:
ENSMUST00000034065,
ENSMUST00000211256,
ENSMUST00000120689,
ENSMUST00000211672
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034065,
ENSMUSP00000147258,
ENSMUSP00000113932,
ENSMUSP00000147809
RefSeq:
NP_780298.2,
NP_001280568.1,
NP_001280566.1,
XP_036009686.1,
XP_036009687.1,
NP_001280567.1,
XP_030099198.1,
XP_006509357.1,
XP_030099199.1,
XP_030099200.1,
XP_036009685.1
|
| Others |
UniRef100:
UniRef100_B2RXQ4,
UniRef100_Q3UXI0,
UniRef100_B2RXX0,
UniRef100_B7ZWK0,
UniRef100_P51954
UniRef90:
UniRef90_Q3UXI0,
UniRef90_P51954
UniRef50:
UniRef50_Q3UXI0,
UniRef50_Q96PY6
UniGene:
Mm.486881
CCDS:
CCDS40347.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员