| Type | Description |
|---|---|
| Definition | neural precursor cell expressed, developmentally down-regulated gene 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:06:00 | We present here the first evidence that the neuroinflammatory mediator IL-1beta facilitates ubiquitin ligase parkin/NEDD8 interactions | 31882005 |
| 2018-03-10 11:27:00 | Downregulation of NEDD8 enhanced the susceptibility of nasopharyngeal carcinoma cells to cisplatin and radiation. | 28569775 |
| 2017-12-30 11:49:00 | Data show that NEDL2 regulates GDNF/Ret/Akt pathway depends on its Nedd8 ligase activity rather than ubiquitin ligase activity. | 27119228 |
| 2017-08-05 11:38:00 | neural precursor cell expressed developmentally downregulated protein 8 (Nedd8) modification of Cul-5 is required for its interaction with TRAF6. | 28522566 |
| 2017-06-03 11:34:00 | Our findings provide mechanistic evidence of the effects of IAP antagonists in combination with NAE inhibitors, and demonstrate the potential of a new combination therapy for cancer. | 27771247 |
| Type | IDs |
|---|---|
| Synonymous | NEDD-8, Rub1 |
| Gene |
UniProtKB-ID:
NEDD8_MOUSE,
Q3UI46_MOUSE
UniprotKB:
P29595,
Q3UI46
UniParc:
UPI0000000235
EMBL:
BC004625,
D10918,
AK147080,
AK146732
Ensembl:
ENSMUSG00000010376
KO:
mmu:18002
|
| Nucleutide sequences |
EMBL-CDS:
BAA01719.1,
AAH04625.1,
BAE27660.1,
BAE27394.1
Ensembl_TRS:
ENSMUST00000010520,
ENSMUST00000163750
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000010520,
ENSMUSP00000130492
RefSeq:
NP_032709.1
|
| Others |
UniRef100:
UniRef100_P29595
UniRef90:
UniRef90_P29595
UniRef50:
UniRef50_P29595
UniGene:
Mm.296566
CCDS:
CCDS49498.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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