| Type | Description |
|---|---|
| Definition | 4-aminobutyrate aminotransferase |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 11:38:00 | ABAT SNP rs1641025 is a potential candidate locus for responsiveness to opioid analgesics in patients with cancer pain. | 30277654 |
| 2016-02-13 11:45:00 | This study utilized ER+ IBC to identify a metagene including ABAT and STC2 as predictive biomarkers for endocrine therapy resistance. | 25771305 |
| 2015-07-20 09:46:00 | A-to-G transition at nucleotide 754 of the human ABAT gene identified in lymphoblast cDNA (c.754A>G) results in substitution of an invariant arginine at amino acid 220 by lysine (p.Arg220Lys). This point mutation results in destabilization of the binding of pyridoxal-5'-phosphate to GABA-transaminase (required for transamination of GABA to succinic semialdehyde) and thus results in GABA-transaminase deficiency. | 25485164 |
| 2013-12-28 11:40:00 | Findings point to a possible role of ABAT gene-regulated GABA catabolism for an altered processing of somatosensory stimuli as a potential vulnerability marker for affective disorders. | 22225676 |
| 2011-08-27 11:31:00 | direct involvement of ABAT in pathways affecting lower esophageal sphincter (LES) control in gastro esophageal reflux disease | 21552517 |
| Type | IDs |
|---|---|
| Synonymous | GABA-AT, GABAT, NPD009 |
| Gene |
UniProtKB-ID:
GABT_HUMAN,
X5D8S1_HUMAN
UniprotKB:
P80404,
X5D8S1
UniParc:
UPI000006D4FC
EMBL:
U80226,
AK290501,
L32961,
BC015628,
S75578,
BC031413,
KJ534758
Ensembl:
ENSG00000183044
KO:
hsa:18
|
| Nucleutide sequences |
EMBL-CDS:
AAH15628.1,
BAF83190.1,
AAD14176.1,
AAH31413.1,
AAA74449.1,
AAB38510.1,
AHW56398.1
Ensembl_TRS:
ENST00000396600,
ENST00000425191,
ENST00000268251
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000411916,
ENSP00000268251,
ENSP00000379845
RefSeq:
NP_001373543.1,
NP_001373538.1,
NP_001373530.1,
NP_001373533.1,
NP_001373542.1,
NP_001373541.1,
NP_001373536.1,
NP_001373537.1,
NP_001373532.1,
NP_001120920.1,
NP_001373529.1,
NP_001373534.1,
NP_001373535.1,
NP_001373531.1,
NP_000654.2,
NP_001373540.1,
NP_001373539.1,
NP_065737.2,
NP_001373545.1,
NP_001373544.1
|
| Others |
UniRef100:
UniRef100_P80404
UniRef90:
UniRef90_P80404
UniRef50:
UniRef50_P80404
UniGene:
Hs.336768
CCDS:
CCDS10534.1
|
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|---|---|---|---|---|---|---|---|---|
| Refseq |
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