| Type | Description |
|---|---|
| Definition | neural precursor cell expressed, developmentally down-regulated 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 15:59:00 | E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation. | 30816303 |
| 2019-07-20 12:40:00 | NEDD4 enhances osteoblast proliferation by removing pSMAD1 activated by TGFbeta1. | 30125728 |
| 2019-07-06 12:44:00 | NEDD4 participates in killing of intracellular bacterial pathogens via autophagy by sustaining the stability of BECN1. | 29251248 |
| 2019-06-29 13:23:00 | This study proved the regulation mechanism that lncRNA SNHG1 negatively regulates p38 MAPK signal pathway through ubiquitination mediated by Nedd4, and thus inhibits osteogenic differentiation of bone marrow mesenchymal stem cells. | 31055087 |
| 2018-12-22 11:54:00 | NEDD4 targets an RNA-binding protein, NANOS2, in spermatogonia to destabilize it, leading to cell differentiation. A NEDD4-mediated mechanism regulates mRNP dynamics, and facilitates spermatogonial progenitor cell homeostasis and viability under normal and stress conditions. | 28585553 |
| Type | IDs |
|---|---|
| Synonymous | AA959633, AL023035, AU019897, E430025J12Rik, EG639396, Gm7265, KIAA0093, Nedd4-1, Nedd4a |
| Gene |
UniProtKB-ID:
NEDD4_MOUSE,
B2RSC8_MOUSE
UniprotKB:
P46935,
B2RSC8
UniParc:
UPI00000EBA2C
EMBL:
AK133838,
AK088620,
AK122203,
AK088767,
U96635,
D85414,
BC138813
Ensembl:
ENSMUSG00000032216
KO:
mmu:17999
|
| Nucleutide sequences |
EMBL-CDS:
BAC40458.1,
AAB63360.1,
BAC65485.1,
BAE21875.1,
BAA12803.1,
BAC40558.1,
AAI38814.1
Ensembl_TRS:
ENSMUST00000034740
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000034740
RefSeq:
NP_035020.2,
NP_001344927.1,
XP_011240974.1
|
| Others |
UniRef100:
UniRef100_P46935
UniRef90:
UniRef90_P46935
UniRef50:
UniRef50_P46935
UniGene:
Mm.279923
CCDS:
CCDS72275.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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