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17995 Ndufv1

17995

Ndufv1

NADH:ubiquinone oxidoreductase core subunit V1

protein-coding

Mus musculus

基因描述

Type Description
Definition NADH:ubiquinone oxidoreductase core subunit V1

研究结论

Date Results Publications
2014-10-11 10:18:00 NDUFV1 knockdown-induced blockage of insulin signaling was released by protein-tyrosine phosphatase 1B knockdown in C2C12 myotubes, and NDUFV1 or SIRT1 knockdown did not affect mitochondria biogenesis during C2C12 myogenesis. myogenesis. 24895128
2013-05-31 07:34:00 The authors use green fluorescent-tagged complex I subunits to determine the kinetics of assembly. Tagged human NDUFV1 can replace endogenous protein in the holo-complex I protein and was also found in complex I subassemblies, suggesting that NDUFV1 may directly incorporate into the holo-enzyme and may also assemble into smaller complexes or in a monomer pool. 23038253
2013-05-31 07:31:00 The authors provide an overview of the function and assembly of human complex I, also known as NADH dehydrogenase (ubiquinone) 1 alpha subcomplex. They discuss its role in oxidative phosphorylation and the implications of complex I deficiency in disease. 22820119
2013-05-31 07:31:00 The authors clone and characterize the human NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial protein, also known as NDUFV1. They identify transcription factor binding sites as well as consensus motifs for NADH, flavin mononucleotide, and iron-sulfur binding sites. The human ortholog has high homology to the cow NDUFV1 protein. 9571201

名称对应

Type IDs
Synonymous CI-51kD
Gene
UniProtKB-ID: NDUV1_MOUSE
UniprotKB: Q91YT0
UniParc: UPI00000255CA
EMBL: BC041682, AK075692, BC014818
Ensembl: ENSMUSG00000037916
KO: mmu:17995
Nucleutide sequences
EMBL-CDS: BAC35893.1, AAH41682.1, AAH14818.1
Ensembl_TRS: ENSMUST00000042497
Protein sequencees
Ensembl_PRO: ENSMUSP00000042967
RefSeq: NP_598427.1
Others
UniRef100: UniRef100_Q91YT0
UniRef90: UniRef90_P49821
UniRef50: UniRef50_P49821
UniGene: Mm.29842
CCDS: CCDS29410.1

全选

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