| Type | Description |
|---|---|
| Definition | Programmed cell death activator egl-1 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:02:00 | Loss of egli-1, the Caenorhabditis elegans Orthologue of a Downstream Target of SMN, Leads to Abnormalities in Sensorimotor Integration. | 31797327 |
| 2017-11-26 01:38:00 | only 1mM DEM caused upregulation of egl-1, a gene controlled by a p53-orthologue, CEP-1.we suppressed GSH biosynthesis in worms by attenuating g-glutamylcysteine synthetase (gcs-1) expression through knockdown commencing right after hatching impaired nematode stress resistance and rendered young adult worms prone to vulval ruptures during egg-laying. | 28086197 |
| 2017-05-27 10:47:00 | A protein interaction cascade involving EGL-1, CED-9, CED-4, and CED-3 results in the activation of the key cell death protease CED-3, which is tightly controlled by multiple positive and negative regulators. | 27516615 |
| 2015-11-21 10:27:00 | LIN-1 binds to, and activates transcription of, the key pro-apoptotic gene egl-1. Our results provide the first evidence that EGF induces PCD at the whole organism level and reveal the molecular basis for the death-promoting function of LIN-3/EGF | 25144461 |
| 2010-10-30 11:09:00 | The transcriptional upregulation of egl-1 in the CEMs in hermaphrodites is necessary, but not sufficient for their death. | 20150917 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
EGL1_CAEEL
UniprotKB:
O61667
UniParc:
UPI00001642A3
EMBL:
AF057309,
BX284605
EnsemblGenome:
WBGene00001170
KO:
cel:CELE_F23B12.9
|
| Nucleutide sequences |
EMBL-CDS:
CAB82213.2,
AAC39023.1
Gene_ORFName:
F23B12.9
EnsemblGenome_TRS:
F23B12.9.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F23B12.9.1
RefSeq:
NP_506575.2
|
| Others |
UniRef100:
UniRef100_O61667
UniRef90:
UniRef90_O61667
UniRef50:
UniRef50_O61667
UniGene:
Cel.19641
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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