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17966 Nbr1

17966

Nbr1

NBR1, autophagy cargo receptor

protein-coding

Mus musculus

基因描述

Type Description
Definition NBR1, autophagy cargo receptor

研究结论

Date Results Publications
2020-10-24 14:05:00 Autophagic Degradation of NBR1 Restricts Metastatic Outgrowth during Mammary Tumor Progression. 32084360
2015-05-23 10:05:00 NBR1 is increased in adipose tissue macrophages in obese mice. The NBR1-MEKK3 complex is important in JNK activation in macrophages. 25043814
2015-05-16 12:08:00 NBR1 phosphorylation by GSK3 at Thr586 prevents the aggregation of ubiquitinated proteins and their selective autophagic degradation. 24879152
2013-08-10 11:51:00 In a mouse model of Huntington disease, NBR1 protein levels were decreased in all brain regions analyzed early in the disease, whereas at late stages they accumulated in the striatum and hippocampus, but not in the cortex. 23295856
2011-04-09 10:39:00 MURF2 expression parallels that of the autophagy-associated proteins LC3, p62/SQSTM1 and nbr1 21185285

名称对应

Type IDs
Synonymous mKIAA0049
Gene
UniProtKB-ID: NBR1_MOUSE, Q6ZQK3_MOUSE, A2A4N5_MOUSE, Q05BC8_MOUSE, A1L329_MOUSE, A2A4N8_MOUSE
UniprotKB: P97432, Q6ZQK3, A2A4N5, Q05BC8, A1L329, A2A4N8
UniParc: UPI000059DD31, UPI000059DD32, UPI00001D49CB, UPI0000483F4A, UPI0000028F5E
EMBL: AK129043, U73039, BC129867, AF227188, AL590994, AL590996, BC129868, BC052709
Ensembl: ENSMUSG00000017119
KO: mmu:17966
Nucleutide sequences
EMBL-CDS: AAF74118.1, AAC53025.1, BAC97853.1, AAH52709.1, AAI29869.1, AAI29868.1
Ensembl_TRS: ENSMUST00000107218, ENSMUST00000103099, ENSMUST00000103098, ENSMUST00000107208, ENSMUST00000123558, ENSMUST00000107213
Protein sequencees
Ensembl_PRO: ENSMUSP00000099387, ENSMUSP00000099388, ENSMUSP00000102836, ENSMUSP00000102826, ENSMUSP00000133619, ENSMUSP00000102831
RefSeq: NP_032702.1, XP_030101501.1, XP_006532494.1, NP_001239149.1, NP_001239151.1, XP_030101502.1, XP_006532496.1, XP_006532493.1, NP_001239152.1, XP_006532495.1, XP_006532497.1, XP_030101499.1, XP_006532498.1
Others
UniRef100: UniRef100_A2A4N8, UniRef100_P97432, UniRef100_A2A4N5, UniRef100_Q05BC8
UniRef90: UniRef90_A2A4N8, UniRef90_P97432
UniRef50: UniRef50_P97432
UniGene: Mm.784, Mm.489817
CCDS: CCDS25475.1

全选

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研究热度

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