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1796 DOK1

1796

DOK1

docking protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition docking protein 1

研究结论

Date Results Publications
2020-10-24 14:09:00 Analysis of the DOK1 gene in breast cancer. 31919752
2020-09-26 13:04:00 Nck adapter proteins promote podosome biogenesis facilitating extracellular matrix degradation and cancer invasion. 31638742
2019-09-21 10:22:00 Decreased DOK1/2 expressions associated with their promoter hypermethylations predict adverse prognosis in AML. 29150948
2017-06-24 11:24:00 Taken together, these results indicate that ATRA-enhanced expression of DOK1 activates PPARgamma leading to inhibition of cell proliferation and enhancement of cell apoptosis in MCF-7 cell. 28396148
2017-02-18 10:24:00 DOK1 was identified as a prognostic factor for non-metastatic CRC, and, via its drugability by PPARgamma-agonist, may constitute a potential target for future cancer treatments. 27428427

名称对应

Type IDs
Synonymous P62DOK, pp62
Gene
UniProtKB-ID: DOK1_HUMAN, Q2TA81_HUMAN, B4DJN1_HUMAN, B3KP83_HUMAN, Q14CB2_HUMAN
UniprotKB: Q99704, Q2TA81, B4DJN1, B3KP83, Q14CB2
UniParc: UPI0000EE257D, UPI00005A674F, UPI000002A833, UPI0000DA6BE4, UPI00001296A9, UPI000022BAE5, UPI00017A72C6
EMBL: AF180527, AK127127, U70987, AK300097, AK296154, AK127656, AF035299, AC005033, BC114440, BC111055, AK055944, BC114497
Ensembl: ENSG00000115325
KO: hsa:1796
Nucleutide sequences
EMBL-CDS: AAB88182.1, AAF19167.1, AAX93224.1, AAC51127.1, AAI14441.1, BAG61898.1, BAG54440.1, AAI11056.1, BAG54544.1, BAG58893.1, BAG51595.1, AAI14498.1
Ensembl_TRS: ENST00000233668, ENST00000409429, ENST00000340004
Protein sequencees
Ensembl_PRO: ENSP00000387016, ENSP00000344330, ENSP00000233668
RefSeq: NP_001305796.1, NP_001372.1, NP_001184189.1, NP_001305795.1, NP_001305797.1, XP_016859017.1, NP_001305798.1
Others
UniRef100: UniRef100_B4DJN1, UniRef100_Q14CB2, UniRef100_B3KP83, UniRef100_Q99704
UniRef90: UniRef90_A0A096MTR9, UniRef90_Q99704, UniRef90_Q14CB2
UniRef50: UniRef50_Q14CB2, UniRef50_Q99704
UniGene: Hs.103854
CCDS: CCDS1954.1, CCDS82474.1, CCDS56125.1

全选

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