| Type | Description |
|---|---|
| Definition | NLR family, apoptosis inhibitory protein 5 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-14 11:40:00 | Six distinct NAIP5 domains contact multiple conserved regions of flagellin, prying NAIP5 into an open and active conformation. | 29146805 |
| 2017-07-22 11:14:00 | These results provide definitive genetic evidence for the important physiological function of NAIPs in antibacterial defense and inflammatory damage-induced lethality in mice. | 27114610 |
| 2014-05-03 11:27:00 | Arsenicals, including arsenic trioxide and sodium arsenite, inhibited activation of the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes. | 24337744 |
| 2013-11-02 10:54:00 | Primary microglial cells have a functional Naip5-NLR family CARD domain containing 4 (NLRC4) inflammasome likely to be important to monitor and clear central nervous system infections by flagellated bacteria. | 23355222 |
| 2013-02-02 11:58:00 | the NAIP5-NLRC4 inflammasome is induced by direct interactions with conserved N- and C-terminal regions of flagellin | 23012363 |
| Type | IDs |
|---|---|
| Synonymous | Birc1e, Lgn1, Naip-rs3 |
| Gene |
UniProtKB-ID:
BIR1E_MOUSE
UniprotKB:
Q9R016
UniParc:
UPI00000E8E54
EMBL:
AF131205,
AY146999,
CT009518,
CT030167,
U66326,
BC070433,
AF135492
Ensembl:
ENSMUSG00000071203
KO:
mmu:17951
|
| Nucleutide sequences |
EMBL-CDS:
AAH70433.1,
AAN60211.1,
AAC52974.1,
AAD56764.1,
AAD56760.1
Ensembl_TRS:
ENSMUST00000049789
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000058611
RefSeq:
XP_017170906.1,
XP_017170904.1,
XP_036013792.1,
XP_011242933.1,
XP_011242930.1,
XP_017170905.1,
NP_035000.2,
XP_011242935.1
|
| Others |
UniRef100:
UniRef100_Q9R016
UniRef90:
UniRef90_Q9R016
UniRef50:
UniRef50_Q9R016
UniGene:
Mm.290476
CCDS:
CCDS26727.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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