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179424 akt-1

179424

akt-1

Serine/threonine-protein kinase akt-1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Serine/threonine-protein kinase akt-1

研究结论

Date Results Publications
2019-09-21 10:46:00 findings suggest that BRAP-2 is required to attenuate the pro-cell survival signals of AKT-1 and PMK-1/SKN-1 to promote DNA damage induced germline apoptosis. 29358669
2017-06-10 11:26:00 the LIN-28/let-7/AKT/DAF-16 axis is a program that plays an important role in balancing reproduction and somatic maintenance. 27730721
2010-01-21 00:00:00 this study shows that akt-1 and akt-2 negatively regulate DNA-damage-induced apoptosis in the C. elegans germline and the antiapoptotic activity of akt-1 is independent of its target gene daf-16 but dependent on cep-1/p53. 17276923
2010-01-21 00:00:00 Modulation of pptr-1 affects insulin/IGF-1 signaling pathway-associated phenotypes including life span, dauer, stress resistance, and fat storage; study shows that PPTR-1 functions by regulating worm AKT-1 phosphorylation at Thr 350. 19249087

名称对应

Type IDs
Gene
UniProtKB-ID: AKT1_CAEEL
UniprotKB: Q17941
UniParc: UPI0000080C1D, UPI0000080469, UPI00000756DF
EMBL: AF072380, AF072379, BX284605
EnsemblGenome: WBGene00000102
KO: cel:CELE_C12D8.10
Nucleutide sequences
EMBL-CDS: AAC62466.1, AAC62467.1, CAA98240.1, CAD44085.1, CAA98238.1
Gene_ORFName: C12D8.10
EnsemblGenome_TRS: C12D8.10a.2, C12D8.10b.2, C12D8.10b.1, C12D8.10c.1, C12D8.10a.1
Protein sequencees
EnsemblGenome_PRO: C12D8.10b.1, C12D8.10a.2, C12D8.10b.2, C12D8.10c.1, C12D8.10a.1
RefSeq: NP_001023646.1, NP_001023645.1, NP_001023647.1
Others
UniRef100: UniRef100_Q17941
UniRef90: UniRef90_Q17941
UniRef50: UniRef50_Q17941
UniGene: Cel.5036

全选

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