| Type | Description |
|---|---|
| Definition | NLR family, apoptosis inhibitory protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-07-22 12:27:00 | Naip1 is uniquely required to detect T3SS needle protein and Naip2 is uniquely required to detect T3SS inner rod protein, but neither Naip1 nor Naip2 is required for detection of flagellin. | 27045008 |
| 2017-07-22 11:14:00 | These results provide definitive genetic evidence for the important physiological function of NAIPs in antibacterial defense and inflammatory damage-induced lethality in mice. | 27114610 |
| 2015-04-11 12:39:00 | An epithelium-intrinsic defense axis recruits NAIP and the NLRC4 inflammasome to promote removal of epithelial cells compromised by pathogen invasion. | 25121751 |
| 2014-05-31 11:48:00 | NAIP/NLRC4 oligomerize, assembling inflammasomes, in the presence of their cognate bacterial ligands. | 24657167 |
| 2013-12-14 10:38:00 | In this study, the the type III secretion system needle protein protein is identified as the agonist for the orphan murine NAIP1 receptor | 24043898 |
| Type | IDs |
|---|---|
| Synonymous | AV364616, Birc1a, D13Lsd1, Naip, Naip-rs1 |
| Gene |
UniProtKB-ID:
BIR1A_MOUSE
UniprotKB:
Q9QWK5
UniParc:
UPI0000D634F4
EMBL:
BC132413,
AF242432,
AF007769,
AF135491
Ensembl:
ENSMUSG00000021640
KO:
mmu:17940
|
| Nucleutide sequences |
EMBL-CDS:
AAB69223.1,
AAF82752.1,
AAD56763.1,
AAI32414.1
Ensembl_TRS:
ENSMUST00000222155,
ENSMUST00000022142
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022142,
ENSMUSP00000152583
RefSeq:
XP_036013791.1,
NP_032696.2
|
| Others |
UniRef100:
UniRef100_Q9QWK5
UniRef90:
UniRef90_Q9QWK5
UniRef50:
UniRef50_Q9R016
UniGene:
Mm.6898
CCDS:
CCDS26729.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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