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17938 Naca

17938

Naca

nascent polypeptide-associated complex alpha polypeptide

protein-coding

Mus musculus

基因描述

Type Description
Definition nascent polypeptide-associated complex alpha polypeptide

研究结论

Date Results Publications
2019-04-06 10:19:00 The data suggest that skNAC and Smyd1 might be major players in the processes of myofibrillogenesis and sarcomerogenesis, probably specifically at later stages. 29499397
2018-05-12 12:02:00 Data show that reduction of alpha chain of nascent polypeptide associated complex (alphaNAC) levels decreased basal expression of Low density lipoprotein receptor-Related Protein 6 (Lrp6) by 30%. 29413898
2015-10-31 11:16:00 the skNAC-Smyd1 complex is involved in transcriptional regulation both via the control of histone methylation and histone (de)acetylation. 26162853
2015-08-15 11:16:00 skNAC binds to the E3 SUMO ligase mammalian Mms21/Nse2 and that knockdown of Nse2 expression inhibits specific aspects of myogenic differentiation, accompanied by a partial blockade of the nuclear-to-cytoplasmic translocation of the skNAC-Smyd1 complex 25002400
2015-02-14 13:40:00 depletion of alphaNAC in multiple types of cancer cells induce typical apoptotic cell death. This anti-apoptotic function is mediated by the FADD/c-Jun N-terminal kinase pathway. 24901053

名称对应

Type IDs
Synonymous AL022831, AL024382, Gm1878, mKIAA0363, skNAC
Gene
UniProtKB-ID: NACAM_MOUSE, NACA_MOUSE
UniprotKB: P70670, Q60817
UniParc: UPI000056536E, UPI00000286DA
EMBL: AC131120, U48363, AK151928, AK169432, AK168607, BC029830, AK168169, BC083340, AK168023, BC099375, AK146197, U22151, AK169435, U48364, AK161678
Ensembl: ENSMUSG00000061315
KO: mmu:17938
Nucleutide sequences
EMBL-CDS: AAB18732.1, AAB18734.1, AAH99375.1, BAE36526.1, AAB80961.1, BAE40130.1, BAE41173.1, AAH83340.1, AAB18733.1, BAE40474.1, BAE40008.1, BAE41176.1, AAH29830.1, BAE30804.1, BAE26971.1
Ensembl_TRS: ENSMUST00000092048, ENSMUST00000073868
Protein sequencees
Ensembl_PRO: ENSMUSP00000089680, ENSMUSP00000073532
RefSeq: NP_001106670.1, NP_038636.2, XP_036011564.1, NP_001269905.1, XP_036011565.1
Others
UniRef100: UniRef100_Q60817, UniRef100_P70670
UniRef90: UniRef90_P70670, UniRef90_Q60817
UniRef50: UniRef50_Q60817, UniRef50_P70670
UniGene: Mm.3746
CCDS: CCDS48723.1, CCDS24258.1

全选

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