| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory subunit 12A |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:02:00 | Augmented contractility of murine femoral arteries in a streptozotocin diabetes model is related to increased threonine phosphorylation of MYPT1. | 30740930 |
| 2020-04-18 10:42:00 | The present results suggested that ROCK1 inhibitor could attenuate mechanical stretchinduced lung endothelial injury and the phosphorylation of MYPT1 in vivo and in vitro. Collectively, the present findings indicated that upregulation of SPHK1 may contribute to VALI in a twohit model. | 31638192 |
| 2019-11-16 11:11:00 | findings reveal a role of Cx40 in regulation of ROCK1 and MLC20 that contributes critically to lung vascular barrier failure in acute lung injury. | 30234377 |
| 2019-11-02 10:09:00 | Phosphorylation of myosin phosphatase targeting subunit 1 (MYPT1) and MYPT1 isoform expression differentially regulates tone via NO/cGMP signaling in cerebral arteries compared to femoral arteries. | 29694711 |
| 2018-12-22 10:45:00 | The findings define the PI3K/NUAK1/MYPT1/MLCP axis as a critical pathway to regulate actomyosin contractility in endothelial cells, supporting vascular patterning and expansion through the control of cell rearrangement. | 30446640 |
| Type | IDs |
|---|---|
| Synonymous | 1200015F06Rik, 5730577I22Rik, AA792106, AV099298, D10Ertd625e, Mypt1 |
| Gene |
UniProtKB-ID:
MYPT1_MOUSE
UniprotKB:
Q9DBR7
UniParc:
UPI00001E4628,
UPI0000028405
EMBL:
CH466539,
AK004785,
BC125381,
BC137630,
AB042280,
AK035230
Ensembl:
ENSMUSG00000019907
KO:
mmu:17931
|
| Nucleutide sequences |
EMBL-CDS:
BAC28990.1,
BAB39108.1,
BAB23563.1,
AAI37631.1,
AAI25382.1,
EDL21703.1
Ensembl_TRS:
ENSMUST00000070663,
ENSMUST00000219263
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000151842,
ENSMUSP00000069257
RefSeq:
NP_001355666.1,
XP_006513392.1,
NP_001355665.1,
XP_006513390.1,
NP_082168.1
|
| Others |
UniRef100:
UniRef100_Q9DBR7
UniRef90:
UniRef90_O14974-2
UniRef50:
UniRef50_O14974
UniGene:
Mm.422959,
Mm.489819
CCDS:
CCDS88083.1,
CCDS36052.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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