Type | Description |
---|---|
Definition | AuTophaGy (yeast Atg homolog) |
Date | Results | Publications |
---|---|---|
2019-12-14 10:51:00 | in the absence of either ATG-18 or EPG-6 autophagy was impaired, and while atg-18 mutant animals showed a short-lived phenotype, lifespan was significantly increased in epg-6 mutant animals. | 30871075 |
2019-07-13 12:05:00 | Using pharmacological and genetic approaches, we found that worms deficient for autophagy were short-lived during starvation and recovered poorly from extended starvation, indicating sensitivity to nutrient stress. Autophagy mutants unc-51/Atg1 and atg-18/Atg18 maintained greater mtDNA content than wild-type worms during starvation, suggesting that autophagy promotes mitochondrial degradation during starvation | 30133321 |
2017-07-01 10:10:00 | ATG-18 acts cell non-autonomously in neuronal and intestinal tissues to maintain C. elegans wildtype lifespan and to respond to DR and IGF-mediated longevity signaling. | 28557996 |
2012-06-09 11:23:00 | The autophagy proteins ATG-18 was sequentially recruited to internalized apoptotic Q cells in the phagocyte. | 22451698 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
ATG18_CAEEL
UniprotKB:
O16466
UniParc:
UPI000007EC9F,
UPI000007F606
EMBL:
BX284605
EnsemblGenome:
WBGene00018294
KO:
cel:CELE_F41E6.13
|
Nucleutide sequences |
EMBL-CDS:
CCD64090.1,
CCD64091.1
Gene_ORFName:
F41E6.13
EnsemblGenome_TRS:
F41E6.13b.1,
F41E6.13a.1
|
Protein sequencees |
EnsemblGenome_PRO:
F41E6.13b.1,
F41E6.13a.1
RefSeq:
NP_741576.1,
NP_741577.1
|
Others |
UniRef100:
UniRef100_O16466
UniRef90:
UniRef90_O16466
UniRef50:
UniRef50_O16466
UniGene:
Cel.17812
|
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