| Type | Description |
|---|---|
| Definition | myosin VI |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:33:00 | Formation of Aberrant Myotubes by Myoblasts Lacking Myosin VI Is Associated with Alterations in the Cytoskeleton Organization, Myoblast Adhesion and Fusion. | 32664530 |
| 2020-08-29 12:47:00 | Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. | 31269433 |
| 2018-06-02 11:22:00 | Loss of MYO6 results in an accumulation of mitophagosomes and an increase in mitochondrial mass. | 29398621 |
| 2018-03-10 11:36:00 | both AKT phosphorylation and RAC-dependent membrane ruffling were markedly reduced by depletion of either APPL1 or MYO6. These results place MYO6 and its binding partners at a central nexus in cellular signaling linking actin dynamics at the cell surface and endosomal signaling in the cell cortex. | 28591580 |
| 2018-02-24 10:17:00 | GIPC1 forms a domain-swapped dimer in an autoinhibited conformation that hinders binding of both PlexinD1 and myosin VI. PlexinD1 binding to GIPC1 releases the autoinhibition, promoting its interaction with myosin VI. GIPCs and myosin VI interact through two distinct interfaces and form an open-ended alternating array. | 28537552 |
| Type | IDs |
|---|---|
| Synonymous |
BC029719,
Myo6 |
| Gene |
UniProtKB-ID:
E9Q175_MOUSE,
V9GX76_MOUSE,
Q8BK95_MOUSE,
E9Q3L1_MOUSE
UniprotKB:
E9Q175,
V9GX76,
Q8BK95,
E9Q3L1
UniParc:
UPI0000DBED97,
UPI00000EB5DC,
UPI00002190FD,
UPI0003B929FE
EMBL:
AC120388,
AC159738,
AK053882
Ensembl:
ENSMUSG00000033577
KO:
mmu:17920
|
| Nucleutide sequences |
EMBL-CDS:
BAC35573.1
Ensembl_TRS:
ENSMUST00000113266,
ENSMUST00000184480,
ENSMUST00000035889
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108891,
ENSMUSP00000139019,
ENSMUSP00000036181
RefSeq:
NP_001034635.2,
XP_006510898.1,
XP_036010565.1,
XP_006510899.1,
XP_006510901.1,
XP_030099964.1
|
| Others |
UniRef100:
UniRef100_Q8BK95,
UniRef100_E9Q3L1,
UniRef100_V9GX76,
UniRef100_E9Q175
UniRef90:
UniRef90_V9GX76,
UniRef90_A0A590UJY4,
UniRef90_Q9UM54-6,
UniRef90_Q9UM54
UniRef50:
UniRef50_Q64331,
UniRef50_A0A0N4VHE1,
UniRef50_Q9UM54
UniGene:
Mm.4040
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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