| Type | Description |
|---|---|
| Definition | myosin VA |
| Date | Results | Publications |
|---|---|---|
| 2020-04-04 12:38:00 | propose that Rab36 stimulates RILPL2 to interact with the myosin-5a globular tail domain (GTD); this interaction then induces exposure of the melanophilin-binding site in the GTD, enabling melanophilin to interact with the GTD and activate myosin-5a motor activity | 31175157 |
| 2018-05-19 10:52:00 | When actin and microtubules were present simultaneously, melanophilin's phosphorylation state enforced track selection of the Rab27a/melanophilin/myosin Va transport complex. | 28559319 |
| 2018-01-27 11:24:00 | In the motor domain-IQ1/Ca(2+)-CaM structure, the N-lobe and the C-lobe of Ca(2+)-CaM adopt an open conformation and grip the C-terminal and the N-terminal portions of the IQ1, respectively. | 27647889 |
| 2017-11-25 13:18:00 | The authors determined crystal structures of MyoVa-globular tail domain bound either to the Spir-2 motif or to Rab11 and show that a Spir-2:MyoVa:Rab11 complex can form. | 27623148 |
| 2017-06-24 10:58:00 | function of two coupled myosin va motors on actin filaments and bundles | 27851945 |
| Type | IDs |
|---|---|
| Synonymous | 9630007J19Rik, AI413174, AI661011, Dbv, MVa, Myo5, MyoVA, Sev-1, d, d-120J, flail, flr |
| Gene |
UniProtKB-ID:
MYO5A_MOUSE,
D3Z4J3_MOUSE,
D3YZ62_MOUSE
UniprotKB:
Q99104,
D3Z4J3,
D3YZ62
UniParc:
UPI000198D091,
UPI0000E445E7,
UPI000198D092
EMBL:
CT033761,
AC133947,
X57377
Ensembl:
ENSMUSG00000034593
KO:
mmu:17918
|
| Nucleutide sequences |
EMBL-CDS:
CAA40651.1
Ensembl_TRS:
ENSMUST00000123128,
ENSMUST00000155282,
ENSMUST00000136731
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000116028,
ENSMUSP00000117493,
ENSMUSP00000120444
RefSeq:
XP_006510890.1,
XP_036010563.1,
XP_006510895.1,
XP_006510893.1,
XP_030099963.1,
XP_006510892.1,
XP_036010564.1,
XP_006510891.1,
NP_034994.2,
XP_006510894.1
|
| Others |
UniRef100:
UniRef100_D3Z4J3,
UniRef100_Q99104,
UniRef100_D3YZ62
UniRef90:
UniRef90_Q99104
UniRef50:
UniRef50_Q99104
UniGene:
Mm.3645
CCDS:
CCDS52860.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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