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17910 Myo15

17910

Myo15

myosin XV

protein-coding

Mus musculus

基因描述

Type Description
Definition myosin XV

研究结论

Date Results Publications
2018-12-22 11:40:00 Gpsm2 defines an approximately 200 nm nanodomain at the tips of stereocilia and this localization requires the presence of Galphai3, myosin 15 and whirlin. 28387217
2016-07-02 10:04:00 Myosin 15 isoforms can navigate between functionally distinct classes of stereocilia, and are independently required to assemble and then maintain the intricate hair bundle architecture. 26302205
2014-11-29 10:08:00 myo15-subfragment 1 is a barbed-end-directed motor that moves actin filaments in a gliding assay using a power stroke of 7.9 nm. Myo15-S1 was rate limited by transit through strongly actin-bound states, similar to other processive myosin motors. 25114250
2013-01-26 10:21:00 Genetic association between myoXV and deafness in a murine model. 22949591
2011-06-25 13:59:00 It was concluded that MyoXVa, whirlin, and Eps8 are integral components of the stereocilia tip complex, where Eps8 is a central actin-regulatory element for elongation of the stereocilia actin core. 21236676

名称对应

Type IDs
Synonymous Myo15a, sh-2, sh2
Gene
UniProtKB-ID: MYO15_MOUSE
UniprotKB: Q9QZZ4
UniParc: UPI0000DBECE2, UPI000049C6AF, UPI00005663C8
EMBL: AY331133, AB014510, AY331132, AF053130, AF144095, AL596090, AL596386
Ensembl: ENSMUSG00000042678
KO: mmu:17910
Nucleutide sequences
EMBL-CDS: AAP88402.1, BAA36582.1, AAC40124.1, AAF05904.1, AAP88403.1
Ensembl_TRS: ENSMUST00000071880, ENSMUST00000094135, ENSMUST00000081823
Protein sequencees
Ensembl_PRO: ENSMUSP00000071777, ENSMUSP00000080507, ENSMUSP00000091686
RefSeq: XP_017169816.1, XP_017169810.1, XP_017169811.1, XP_017169819.1, XP_017169809.1, NP_001096641.1, XP_017169817.1, XP_017169818.1, XP_017169814.1, XP_017169820.1, NP_874357.2, NP_034992.2, XP_017169808.1, XP_017169815.1, XP_017169813.1, XP_017169812.1
Others
UniRef100: UniRef100_Q9QZZ4
UniRef90: UniRef90_Q9QZZ4
UniRef50: UniRef50_Q9QZZ4
UniGene: Mm.89960
CCDS: CCDS24792.1, CCDS24793.1, CCDS48811.1

全选

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