| Type | Description |
|---|---|
| Definition | Myotonic dystrophy-Related, Cdc42-binding Kinase homolog;Protein kinase C;Serine/threonine-protein kinase mrck-1 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 11:59:00 | MRCK-1 is required for activation of contractile actomyosin dynamics and elevated cortical tension in the apical cell cortex of endoderm precursor cells. MRCK-1 is apically localized by active Cdc42 at the external, cell-cell contact-free surfaces of apically constricting cells, downstream of cell fate determination mechanisms. | 27451898 |
| 2010-01-21 00:00:00 | Data show that combined loss of ROCK and PAK, or ROCK and MRCK, completely prevented embryonic elongation, but a constitutively active form of MLC-4 could only rescue a lack of MRCK. | 19675126 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
MRCK_CAEEL,
A0A0K3AUZ7_CAEEL,
A0A0K3AS73_CAEEL,
A0A0K3AVQ9_CAEEL,
A0A0K3AY02_CAEEL
UniprotKB:
O01583,
A0A0K3AUZ7,
A0A0K3AS73,
A0A0K3AVQ9,
A0A0K3AY02
UniParc:
UPI0000078363,
UPI0005CDCF95,
UPI00003E5918,
UPI0005CDCFB9,
UPI0005CDCFAA
EMBL:
BX284605,
FO081273
EnsemblGenome:
WBGene00006437
KO:
cel:CELE_K08B12.5
|
| Nucleutide sequences |
EMBL-CDS:
CCD70382.1,
CTQ86840.1,
CTQ86841.1,
CTQ86842.1,
CTQ86843.1
Gene_ORFName:
K08B12.5,
CELE_K08B12.5,
K08B12.5,
K08B12.5,
CELE_K08B12.5,
CELE_K08B12.5,
K08B12.5,
CELE_K08B12.5,
K08B12.5
EnsemblGenome_TRS:
K08B12.5a.2,
K08B12.5a.1
|
| Protein sequencees |
EnsemblGenome_PRO:
K08B12.5a.2,
K08B12.5a.1
RefSeq:
NP_001300144.1,
NP_001300142.1,
NP_001300143.1,
NP_504599.2,
NP_001300141.1
|
| Others |
UniRef100:
UniRef100_O01583,
UniRef100_A0A0K3AUZ7
UniRef90:
UniRef90_O01583
UniRef50:
UniRef50_O01583
UniGene:
Cel.20082
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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