| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory subunit 15A |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:26:00 | Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS. | 31837419 |
| 2020-05-09 11:25:00 | A2aR effectively downregulated p-eIF2alpha/eIF2alpha, XBP-1, XBP-1s, BIP, and CHOP levels, whereas GADD34 was upregulated. | 30417358 |
| 2019-01-12 11:15:00 | Depletion of HES1 increased cell death in response to endoplasmic reticulum stress in mouse and human cells, in a manner that depended on the pro-apoptotic gene growth arrest and DNA damage-inducible protein GADD34. | 29491143 |
| 2018-12-01 10:55:00 | Findings highlight that the phosphatase regulator, GADD34, also functions as a kinase scaffold in response to chronic oxidative stress and recruits CK1 and oxidized TDP-43 to facilitate its phosphorylation, as seen in TDP-43 proteinopathies. | 29109149 |
| 2018-07-14 12:13:00 | established Neuro2a cells with edited GADD34 and ATF4/GADD34 genes and found that ATF4 acts as a proapoptotic factor, but GADD34 depletion did not attenuate the expression of cleaved caspase-3 induced by tunicamycin treatment. | 28825160 |
| Type | IDs |
|---|---|
| Synonymous | 9630030H21, Gadd34, Myd116 |
| Gene |
UniProtKB-ID:
PR15A_MOUSE,
B2RRL7_MOUSE
UniprotKB:
P17564,
B2RRL7
UniParc:
UPI00015DF0B1,
UPI00000272F1
EMBL:
BC138485,
BC138486,
AK079339,
AK154697,
AK167317,
X51829
Ensembl:
ENSMUSG00000040435
KO:
mmu:17872
|
| Nucleutide sequences |
EMBL-CDS:
CAA36128.1,
BAC37613.1,
BAE39419.1,
BAE32770.1,
AAI38487.1,
AAI38486.1
Ensembl_TRS:
ENSMUST00000167273,
ENSMUST00000042105
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000128497,
ENSMUSP00000049488
RefSeq:
NP_032680.1
|
| Others |
UniRef100:
UniRef100_P17564
UniRef90:
UniRef90_P17564
UniRef50:
UniRef50_O75807
UniGene:
Mm.4048
CCDS:
CCDS21249.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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