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1787 TRDMT1

1787

TRDMT1

tRNA aspartic acid methyltransferase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition tRNA aspartic acid methyltransferase 1

研究结论

Date Results Publications
2021-02-06 13:52:00 Trdmt1 3'-untranslated region functions as a competing endogenous RNA in leukemia HL-60 cell differentiation. 33331537
2020-06-27 12:22:00 TRDMT1 has a role in 5-methylcytosine modification of mRNA and in HEK293 cell proliferation and migration 31570165
2017-07-15 12:19:00 Data suggest that, upon HIV-1 infection, DNMT2 is re-localized from the nucleus to cytoplasmic stress granules where DNMT2 methylates HIV-1 messenger RNA; this methylation increases the stability of the HIV-1 RNA genome and up-regulates virus replication; thus, DNMT2 appears to facilitate HIV-1 infection. 28476776
2016-01-16 12:02:00 The strong effect of some of the somatic cancer mutations on DNMT2 activity suggests that these mutations have a functional role in tumorigenesis. 25747896
2015-08-08 11:25:00 DNMT1, DNMT2 and DNMT3A may play important roles in gastric cancer carcinogenesis. 22942708

名称对应

Type IDs
Synonymous DMNT2, DNMT2, MHSAIIP, PUMET, RNMT1
Gene
UniProtKB-ID: TRDMT_HUMAN, Q6ICS7_HUMAN, Q7Z3E4_HUMAN, B4DQZ2_HUMAN, A0A0U1U562_HUMAN
UniprotKB: O14717, Q6ICS7, Q7Z3E4, B4DQZ2, A0A0U1U562
UniParc: UPI000002A831, UPI00001A9D3A, UPI000002A832, UPI0000129698, UPI0005D024B4, UPI000002A830, UPI00017A7C51, UPI000002A82E, UPI000002A82F
EMBL: HQ637549, AF329941, AC067747, AF012128, AF329944, AK299027, CH471072, AF329943, BC047733, AK291417, AF045888, AJ223333, BX537961, EF444974, AF329942, AF329940, AL133415, CR450316
Ensembl: ENSG00000107614
KO: hsa:1787
Nucleutide sequences
EMBL-CDS: ACA05985.1, AAK68037.1, AAH47733.1, ACA05986.1, AAK68036.1, AAK68035.1, AAC39764.1, AAK68033.1, EAW86218.1, ACA05980.1, AAK68034.1, EAW86219.1, AAC51939.1, ACA05984.1, CAA11272.1, EAW86217.1, BAF84106.1, ACA05987.1, ACA05983.1, CAG29312.1, ACA05981.1, CAD97925.1, BAG61104.1, AER93400.1
Gene_ORFName: hCG_23994
Ensembl_TRS: ENST00000495022, ENST00000377799, ENST00000354631
Protein sequencees
Ensembl_PRO: ENSP00000367030, ENSP00000417594, ENSP00000346652
RefSeq: NP_001338148.1, XP_016871298.1, XP_005252432.1, XP_005252435.1, XP_016871301.1, XP_024303625.1, NP_001338149.1, XP_011517645.1, XP_016871290.1, XP_011517646.1, XP_016871291.1, NP_001307936.1, NP_001338151.1, XP_011517647.1, XP_024303626.1, NP_001338150.1, XP_024303624.1, NP_001307935.1, XP_016871293.1, NP_001338152.1, XP_016871299.1, XP_016871295.1, XP_024303623.1, NP_004403.1, XP_016871292.1, XP_005252431.1
Others
UniRef100: UniRef100_B4DQZ2, UniRef100_O14717, UniRef100_A0A0U1U562, UniRef100_Q7Z3E4
UniRef90: UniRef90_A0A6J3F357, UniRef90_Q7Z3E4, UniRef90_O14717
UniRef50: UniRef50_O14717, UniRef50_O14717-5
UniGene: Hs.351665
CCDS: CCDS7114.1

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