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17865 Mybl2

17865

Mybl2

myeloblastosis oncogene-like 2

protein-coding

Mus musculus

基因描述

Type Description
Definition myeloblastosis oncogene-like 2

研究结论

Date Results Publications
2020-08-01 14:20:00 Protein-protein interaction studies showed that YAP binds directly to B-MYB, a subunit of MMB, in a manner dependent on the YAP WW domains and a PPXY motif in B-MYB. Disruption of the interaction by overexpression of the YAP binding domain of B-MYB strongly inhibits the proliferation of cardiomyocytes. 32469866
2017-03-18 12:40:00 Downregulation of B-myb induced senescence by upregulation of p22(phox) and activation of the pathway 27878894
2014-04-26 11:40:00 B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development. 24516162
2013-05-04 11:21:00 MYBL2 haploinsufficiency increases susceptibility to age-related haematopoietic neoplasia. 22910183
2013-04-27 11:51:00 Results coupled with functional studies demonstrate that B-MYB not only controls and accelerates cell cycle progression in ESCs it contributes to fate decisions and maintenance of pluripotent stem cell identity. 22936984

名称对应

Type IDs
Synonymous B-Myb, Bmyb
Gene
UniProtKB-ID: MYBB_MOUSE
UniprotKB: P48972
UniParc: UPI0000003F70
EMBL: X73028, X70472, AK028497, BC050842
Ensembl: ENSMUSG00000017861
KO: mmu:17865
Nucleutide sequences
EMBL-CDS: BAC25979.1, CAA49898.1, AAH50842.1, CAA51511.1
Ensembl_TRS: ENSMUST00000018005
Protein sequencees
Ensembl_PRO: ENSMUSP00000018005
RefSeq: XP_006498939.1, XP_006498938.1, XP_006498936.1, XP_006498941.1, NP_032678.1
Others
UniRef100: UniRef100_P48972
UniRef90: UniRef90_P48972
UniRef50: UniRef50_P48972
UniGene: Mm.4594
CCDS: CCDS17006.1

全选

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研究热度

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