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178640 unc-60

178640

unc-60

Actin-depolymerizing factor 1;Actin-depolymerizing factor 2

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Actin-depolymerizing factor 1;Actin-depolymerizing factor 2

研究结论

Date Results Publications
2014-05-24 10:14:00 The invadopodial membrane is a specialized compartment whose recycling to form dynamic, functional invadopodia is dependent on localized F-actin disassembly by unc-60a. 24662568
2010-01-21 00:00:00 UNC-60A and UNC-60B play distinct roles in specific aspects of actin reorganization in vivo 12679387
2010-01-21 00:00:00 These results indicate that cofilin severs the actin filament by a mechanism of allosteric and cooperative destabilization. 17134718
2010-01-21 00:00:00 results suggest that an optimal level of actin-filament-severing activity of ADF/cofilin is required for assembly of actin networks in the somatic gonad 18653537
2010-01-21 00:00:00 Data show that UNC-87 competes with ADF/cofilin (unc-60) for binding to actin filaments and inhibits ADF/cofilin-dependent filament severing and depolymerization in vitro. 17684058

名称对应

Type IDs
Synonymous CELE_F53E2.2, F53E2.2
Gene
UniProtKB-ID: ADF2_CAEEL
UniprotKB: Q07749
UniParc: UPI0000125530
EMBL: FO080816, L18963
EnsemblGenome: WBGene00006794
KO: cel:CELE_C38C3.5
Nucleutide sequences
EMBL-CDS: AAC14457.1, CCD67023.1
Gene_ORFName: C38C3.5
EnsemblGenome_TRS: C38C3.5.1
Protein sequencees
EnsemblGenome_PRO: C38C3.5.1
RefSeq: NP_503427.2
Others
UniRef100: UniRef100_Q07749
UniRef90: UniRef90_Q07749
UniRef50: UniRef50_Q07749
UniGene: Cel.17967

全选

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研究热度

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