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178458 rho-1

178458

rho-1

Ras-like GTP-binding protein rhoA

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition Ras-like GTP-binding protein rhoA

研究结论

Date Results Publications
2019-11-09 13:05:00 Genetic interactions are consistent with RHO-1 and RHGF-1 acting with UNC-5, as well as with a parallel pathway, to regulate protrusion. The cytoskeletal interacting molecule UNC-33/CRMP was required for RHO-1 activity to inhibit MT accumulation, suggesting that UNC-33/CRMP might act downstream of RHO-1. In sum, these studies describe a new role of RHO-1 and RHGF-1 in regulation of growth cone protrusion by UNC-6/Netrin 31233487
2019-09-28 10:26:00 excitable RhoA dynamics are a common driver for pulsed contractility that can be tuned or coupled differently to actomyosin dynamics to produce a diversity of morphogenetic outcomes. 30275107
2019-04-13 10:07:00 RHO-1 activity is regulated by SAX-3/ROBO acting on the RhoGAP HUM-7. 30389847
2019-03-09 10:13:00 negative regulation of dopamine signalling via DAT-1 is necessary for the neuronal RHO-1 pathway to regulate locomotion. 30240421
2018-01-13 12:01:00 Here, the authors report that in the Caenorhabditis elegans zygote, feedback between active RhoA and myosin induces a contractile instability in the actomyosin cell cortex. 28117665

名称对应

Type IDs
Gene
UniProtKB-ID: RHO1_CAEEL
UniprotKB: Q22038
UniParc: UPI0000123DA6
EMBL: L36965, AL132952
EnsemblGenome: WBGene00004357
KO: cel:CELE_Y51H4A.3
Nucleutide sequences
EMBL-CDS: AAC37216.1, CAB63379.1
Gene_ORFName: Y51H4A.3
EnsemblGenome_TRS: Y51H4A.3a.1
Protein sequencees
EnsemblGenome_PRO: Y51H4A.3a.1
RefSeq: NP_502959.1
Others
UniRef100: UniRef100_Q22038
UniRef90: UniRef90_Q22038
UniRef50: UniRef50_Q22038
UniGene: Cel.17449

全选

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研究热度

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