sas-6 - Spindle assembly abnormal protein 6-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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178345 sas-6

基因描述

Type	Description
Definition	Spindle assembly abnormal protein 6

研究结论

Date	Results	Publications
2020-11-16 01:05:00	The PP2A-mediated dephosphorylation promotes centriolar targeting of SAS-5 and ensures SAS-6 delivery to the site of centriole assembly.	21497765
2016-07-28 13:23:00	SAS-6 is a component that is required for daughter centriole formation in C. elegans. SAS-6 is a coiled-coil protein that is recruited to centrioles at the onset of the centrosome duplication cycle.	15665853
2013-07-13 11:13:00	Direct interactions of the SAS-6 coiled coil with ZYG-1 and SAS-5 are required to recruit SAS-6 to the mother centriole.	23673331
2013-02-09 10:24:00	It was demonstrated that the short SAS-5 C-terminal domain (residues 390-404) specifically binds to a narrow central region (residues 275-288) of the SAS-6 coiled coil.	23064147
2010-02-01 11:44:00	Study demonstrates that the kinase ZYG-1 phosphorylates the coiled-coil protein SAS-6 at serine 123 in vitro; this phosphorylation event is crucial for centriole formation in vivo.	20059959

名称对应

Type	IDs
Gene	UniProtKB-ID: SAS6_CAEEL UniprotKB: O62479 UniParc: UPI000007B7D7 EMBL: AL021492 EnsemblGenome: WBGene00012888 KO: cel:CELE_Y45F10D.9
Nucleutide sequences	EMBL-CDS: CAA16384.1 Gene_ORFName: Y45F10D.9 EnsemblGenome_TRS: Y45F10D.9.1
Protein sequencees	EnsemblGenome_PRO: Y45F10D.9.1 RefSeq: NP_502660.1
Others	UniRef100: UniRef100_O62479 UniRef90: UniRef90_O62479 UniRef50: UniRef50_O62479 UniGene: Cel.9095

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
30837637	A dynamically interacting flexible loop assists oligomerisation of the Caenorhabditis elegans centriolar protein SAS-6. Sci Rep Julia M C Busch , MichÃ¨le C Erat , Iris D Blank , Maria Musgaard , Philip C Biggin , Ioannis Vakonakis	2019-03-05	-
28743734	Centriole translocation and degeneration during ciliogenesis in Caenorhabditis elegans neurons. EMBO J Wenjing Li , Peishan Yi , Zhiwen Zhu , Xianliang Zhang , Wei Li , Guangshuo Ou	2017-09-01	-
23798409	Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry. Proc. Natl. Acad. Sci. U.S.A. Manuel Hilbert , MichÃ¨le C Erat , Virginie Hachet , Paul Guichard , Iris D Blank , Isabelle FlÃ¼ckiger , Leanne Slater , Edward D Lowe , Georgios N Hatzopoulos , Michel O Steinmetz , Pierre GÃ¶nczy , Ioannis Vakonakis	2013-07-09	-
23673331	Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Dev. Cell Molly M Lettman , Yao Liang Wong , Valeria Viscardi , Sherry Niessen , Sheng-Hong Chen , Andrew K Shiau , Huilin Zhou , Arshad Desai , Karen Oegema	2013-05-13	zyg-1, sas-6
23064147	SAS-6 coiled-coil structure and interaction with SAS-5 suggest a regulatory mechanism in C. elegans centriole assembly. EMBO J. Renping Qiao , Gabriela Cabral , Molly M Lettman , Alexander Dammermann , Gang Dong	2012-11-14	-
21497765	PP2A phosphatase acts upon SAS-5 to ensure centriole formation in C. elegans embryos. Dev. Cell Daiju Kitagawa , Isabelle FlÃ¼ckiger , Jolanta Polanowska , Debora Keller , JÃ©rÃ´me Reboul , Pierre GÃ¶nczy	2011-04-19	pptr-2
21277013	Structural basis of the 9-fold symmetry of centrioles. Cell Daiju Kitagawa , Ioannis Vakonakis , Natacha Olieric , Manuel Hilbert , Debora Keller , Vincent Olieric , Miriam Bortfeld , MichÃ¨le C Erat , Isabelle FlÃ¼ckiger , Pierre GÃ¶nczy , Michel O Steinmetz	2011-02-04	-
20059959	Phosphorylation of SAS-6 by ZYG-1 is critical for centriole formation in C. elegans embryos. Dev. Cell Daiju Kitagawa , Coralie Busso , Isabelle FlÃ¼ckiger , Pierre GÃ¶nczy	2009-12-01	zyg-1, sas-6
19109417	Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches. Mol. Biol. Cell Anthony Essex , Alexander Dammermann , Lindsay Lewellyn , Karen Oegema , Arshad Desai	2009-02-01	-
19123269	Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Nat Methods Nicolas Simonis , Jean-FranÃ§ois Rual , Anne-Ruxandra Carvunis , Murat Tasan , Irma Lemmens , Tomoko Hirozane-Kishikawa , Tong Hao , Julie M Sahalie , Kavitha Venkatesan , Fana Gebreab , Sebiha Cevik , Niels Klitgord , Changyu Fan , Pascal Braun , Ning Li , Nono Ayivi-Guedehoussou , Elizabeth Dann , Nicolas Bertin , David Szeto , AmÃ©lie Dricot , Muhammed A Yildirim , Chenwei Lin , Anne-Sophie de Smet , Huey-Ling Kao , Christophe Simon , Alex Smolyar , Jin Sook Ahn , Muneesh Tewari , Mike Boxem , Stuart Milstein , Haiyuan Yu , Matija Dreze , Jean Vandenhaute , Kristin C Gunsalus , Michael E Cusick , David E Hill , Jan Tavernier , Frederick P Roth , Marc Vidal	2009-01-01	-

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