| Type | Description |
|---|---|
| Definition | dynein cytoplasmic 1 light intermediate chain 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-20 10:42:00 | Cortically localized dynein, essential for maintaining correct spindle orientation, consists majorly of LIC2-dynein, which interacts with cortical 14-3-3 epsilon- zeta and Par3, conserved proteins required for orienting the spindle. | 28003657 |
| 2017-08-05 12:50:00 | This study uncovers a novel functional hierarchy during mitotic checkpoint inactivation between the closely related but homologous LIC subunits of cytoplasmic dynein. | 27441562 |
| 2017-06-24 10:44:00 | These results suggest that cytoplasmic dynein 1 binds to BRCA2 through the latter's centrosomal localization signal and BRCA2 mediates the cohesion between centrosomes during the S phase, potentially serving as a cell-cycle checkpoint. | 27433848 |
| 2015-03-21 13:18:00 | although dynein lacking light intermediate chains (LICs) drives microtubule gliding at normal rates, the LICs are required for the formation and maintenance of a bipolar spindle. | 25422374 |
| 2011-05-28 10:13:00 | using a variety of complementary approaches, our results indicate a novel specific role for the LICs in dynein recruitment to components of the late endocytic pathway. | 21169557 |
| Type | IDs |
|---|---|
| Synonymous | DNCLI2, LIC2 |
| Gene |
UniProtKB-ID:
DC1L2_HUMAN,
A0A024R6Z0_HUMAN,
Q63HJ8_HUMAN
UniprotKB:
O43237,
A0A024R6Z0,
Q63HJ8
UniParc:
UPI0000129A0D,
UPI00017A84C5,
UPI0000229EFC
EMBL:
AF035812,
CH471092,
AC044802,
AC018557,
AK291766,
BX648863,
BC025959,
AK303031
Ensembl:
ENSG00000135720
KO:
hsa:1783
|
| Nucleutide sequences |
EMBL-CDS:
EAW83039.1,
BAF84455.1,
AAB88513.1,
AAH25959.1,
BAG64156.1,
EAW83040.1,
CAH56157.1
Gene_ORFName:
hCG_28828
Ensembl_TRS:
ENST00000443351,
ENST00000258198
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394289,
ENSP00000258198
RefSeq:
NP_001310884.1,
NP_006132.1,
XP_016878497.1,
NP_001273086.1
|
| Others |
UniRef100:
UniRef100_Q63HJ8,
UniRef100_O43237
UniRef90:
UniRef90_Q63HJ8,
UniRef90_O43237
UniRef50:
UniRef50_O43237,
UniRef50_A0A3B4CVF6
UniGene:
Hs.369068
CCDS:
CCDS10818.1,
CCDS67049.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员