| Type | Description |
|---|---|
| Definition | Protein lin-3 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:13:00 | Epidermal Growth Factor Signaling Promotes Sleep through a Combined Series and Parallel Neural Circuit. | 31839447 |
| 2017-05-27 10:20:00 | Even a short 58 bp cis-regulatory fragment from C. angaria with this single E-box is able to replace the three transcription factor binding sites at the endogenous C. elegans lin-3 locus, resulting in the wild-type expression level. Thus, regulatory evolution occurring in cis within a 58 bp lin-3 fragment, results in a strict requirement for the NHR binding site and a second E-box in C. elegans | 27588814 |
| 2015-11-21 10:27:00 | LIN-1 binds to, and activates transcription of, the key pro-apoptotic gene egl-1 Our results provide the first evidence that EGF induces PCD at the whole organism level and reveal the molecular basis for the death-promoting function of LIN-3/EGF | 25144461 |
| 2012-03-24 10:30:00 | widespread ectopic expression of a lin-3 growth factor mRNA at concentrations much lower than that in the normal domain of expression can abnormally activate the Ras pathway and alter cell fates | 22242000 |
| 2011-07-16 11:30:00 | LIN-56 and LIN-15A associate in a nuclear complex that inhibits vulval specification by repressing lin-3 EGF expression. | 21196525 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LIN3_CAEEL,
A0A061AEC4_CAEEL,
A0A061AD43_CAEEL
UniprotKB:
Q03345,
A0A061AEC4,
A0A061AD43
UniParc:
UPI000499F23F,
UPI000002AD4A,
UPI0000DF0451,
UPI00049A92FE,
UPI000012E69F,
UPI0001721C6A,
UPI00015BFC0F,
UPI000002AD49
EMBL:
X68070,
AL032641,
BX284604
EnsemblGenome:
WBGene00002992
KO:
cel:CELE_F36H1.4
|
| Nucleutide sequences |
EMBL-CDS:
CAD27623.1,
CAQ35042.1,
CAP03133.1,
CAA48207.1,
CAA92997.2,
CAD30434.1,
CAL44969.1,
CDR32814.1,
CDR32815.1
Gene_ORFName:
F36H1.4,
F36H1.4,
CELE_F36H1.4,
CELE_F36H1.4,
F36H1.4
EnsemblGenome_TRS:
F36H1.4f.1,
F36H1.4e.1,
F36H1.4c.1,
F36H1.4b.2,
F36H1.4f.2,
F36H1.4a.1,
F36H1.4b.1,
F36H1.4d.2,
F36H1.4d.1
|
| Protein sequencees |
EnsemblGenome_PRO:
F36H1.4f.1,
F36H1.4e.1,
F36H1.4c.1,
F36H1.4b.2,
F36H1.4f.2,
F36H1.4a.1,
F36H1.4b.1,
F36H1.4d.2,
F36H1.4d.1
RefSeq:
NP_001122777.1,
NP_001367187.1,
NP_001367146.1,
NP_741488.1,
NP_741489.1,
NP_001294020.1,
NP_001294021.1,
NP_741490.1
|
| Others |
UniRef100:
UniRef100_A0A061AEC4,
UniRef100_A0A061AD43,
UniRef100_Q03345
UniRef90:
UniRef90_Q03345
UniRef50:
UniRef50_Q03345
UniGene:
Cel.18204
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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