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1780 DYNC1I1

1780

DYNC1I1

dynein cytoplasmic 1 intermediate chain 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition dynein cytoplasmic 1 intermediate chain 1

研究结论

Date Results Publications
2020-09-26 13:02:00 TNPO2 operates downstream of DYNC1I1 and promotes gastric cancer cell proliferation and inhibits apoptosis. 31605449
2019-03-09 11:07:00 Thus, these findings demonstrate a tumor-suppressive function of DYNC1I1, and uncover new mechanistic insights into SK2 regulation which may have implications in targeting this enzyme as a therapeutic strategy in glioblastoma 30250299
2015-06-27 13:39:00 SQSTM1 is required for proper dynein motility and trafficking along microtubules. 25015291
2015-04-04 11:41:00 Deletions of the exons with regulatory potential of DYNC1I1 are an example of the emerging role of exonic enhancer elements and their implications in congenital malformation syndromes 25231166
2014-11-22 11:19:00 Genome sequencing of the deletion breakpoints showed that the DLX5 and DLX6 genes are disomic but the putative DYNC1I1 exon 15 and 17 enhancers are deleted. 24459211

名称对应

Type IDs
Synonymous DNCI1, DNCIC1
Gene
UniProtKB-ID: DC1I1_HUMAN, A4D1I7_HUMAN, Q8N542_HUMAN
UniprotKB: O14576, A4D1I7, Q8N542
UniParc: UPI000002A869, UPI0002064F5A, UPI0000129A01, UPI0000E215E9, UPI000006CCDC, UPI000002A86A
EMBL: AK313148, AF063228, AC091779, BC032945, AC022261, BC022540, AC002452, CH471091, AC002540, AK091339, AF123074, AK297427, CH236949
Ensembl: ENSG00000158560
KO: hsa:1780
Nucleutide sequences
EMBL-CDS: EAW76753.1, AAB70113.1, AAC33443.1, AAH22540.1, BAG59855.1, AAD26852.1, BAC03639.1, AAB67047.2, EAL24126.1, BAG35966.1, EAW76755.1, AAH32945.1
Gene_ORFName: hCG_40542, tcag7.305
Ensembl_TRS: ENST00000447467, ENST00000630942, ENST00000457059, ENST00000324972, ENST00000359388, ENST00000437599
Protein sequencees
Ensembl_PRO: ENSP00000352348, ENSP00000486363, ENSP00000392337, ENSP00000398118, ENSP00000320130, ENSP00000412444
RefSeq: NP_001265350.1, NP_001265351.1, NP_004402.1, NP_001129029.1, NP_001129028.1
Others
UniRef100: UniRef100_Q8N542, UniRef100_O14576
UniRef90: UniRef90_O14576, UniRef90_O14576-4
UniRef50: UniRef50_O14576-4, UniRef50_O14576
UniGene: Hs.440364
CCDS: CCDS64718.1, CCDS64719.1, CCDS47645.1, CCDS5644.1, CCDS47646.1

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