| Type | Description |
|---|---|
| Definition | Protein lgg;Protein lgg-2 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:31:00 | LGG-1 is involved in the exposure of the 'eat-me signal' phosphatidylserine at the surface of the apoptotic cell to allow its recognition by the phagocytic cell, whereas LGG-2 is involved in later steps of phagocytosis to allow efficient cell corpse clearance by mediating the maturation/degradation of the phagosome. | 30160610 |
| 2020-01-25 14:44:00 | we found that LGG-2/LC3 regulates Nematocida colonization inside intestinal cells. Interestingly, LGG-2/LC3 regulates intracellular colonization only in the HW strain, and not in N2. Altogether these results demonstrate that there is natural genetic variation in an LGG-2-dependent process that regulates microsporidia colonization inside intestinal cells, although not microsporidia clearance | 31013330 |
| 2019-06-29 10:32:00 | This work analyzed in apoptotic cell and phagocytic cell the localization of the two homologs of LC3/GABARAP proteins, namely, LGG-1 and LGG-2. | 30610704 |
| 2019-05-11 10:18:00 | Our results indicate that an ARF-like GTPase gene product, ARL-8, mitigates endocytic Ab neurodegeneration in a VPS-41-dependent manner, rather than through RAB-7 and AP3 as with alpha-synuclein..we demonstrate that the LC3 orthologue, LGG-2, plays a critical role in Ab toxicity with ARL-8. | 30508205 |
| 2016-04-30 10:22:00 | Data show the N-terminal of LGG-1 and LGG-2 adopts the closed and open form, respectively. They have distinct binding pockets that prefer different residues, influencing binding specificity and differential interaction with autophagy proteins. | 26687600 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
LGG2_CAEEL,
E2JKY9_CAEEL
UniprotKB:
Q23536,
E2JKY9
UniParc:
UPI0001E560F8,
UPI000013B2AB
EMBL:
BX284604,
Z69385
EnsemblGenome:
WBGene00002981
KO:
cel:CELE_ZK593.6
|
| Nucleutide sequences |
EMBL-CDS:
CAA93421.1,
CBX25215.1
Gene_ORFName:
ZK593.6,
CELE_ZK593.6,
ZK593.6
EnsemblGenome_TRS:
ZK593.6a.1,
ZK593.6a.2
|
| Protein sequencees |
EnsemblGenome_PRO:
ZK593.6a.2,
ZK593.6a.1
RefSeq:
NP_001255524.1,
NP_001255523.2
|
| Others |
UniRef100:
UniRef100_Q23536
UniRef90:
UniRef90_Q23536
UniRef50:
UniRef50_Q23536
UniGene:
Cel.18191
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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