| Type | Description |
|---|---|
| Definition | DyNactin Complex component |
| Date | Results | Publications |
|---|---|---|
| 2017-08-26 11:09:00 | we dissect the role of dynactin's microtubule binding activity, located in the p150 CAP-Gly domain and an adjacent basic patch, in the C. elegans zygote. Our results suggest that p150 GAP-Gly domain binding to microtubules promotes initiation of dynein-mediated organelle transport in the dividing one-cell embryo, and that this function of p150 is critical for generating cytoplasmic pulling forces for centrosome | 28759579 |
| 2013-09-07 11:44:00 | results suggest that decreased expression of dynactin 1 induces motor neuron degeneration and that the transport of autophagosomes is a novel and substantial therapeutic target for motor neuron degeneration | 23408943 |
| 2011-06-04 10:16:00 | putative UNC-104 interactors, namely UNC-16(JIP3), DNC-1(DCTN1/Glued) and SYD-2(Liprin-alpha), inherit different functions in steering UNC-104 to specific sub-cellular locations in the neuron | 21195138 |
| 2010-01-21 00:00:00 | Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos | 18187449 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
L8EC32_CAEEL,
E2JKZ0_CAEEL,
L8E938_CAEEL,
E2JKY8_CAEEL,
Q23542_CAEEL
UniprotKB:
L8EC32,
E2JKZ0,
L8E938,
E2JKY8,
Q23542
UniParc:
UPI0002AB0D47,
UPI0001E560F7,
UPI0002AB1249,
UPI0001E560F6,
UPI000007C4B9
EMBL:
BX284604
EnsemblGenome:
WBGene00001017
KO:
cel:CELE_ZK593.5
|
| Nucleutide sequences |
EMBL-CDS:
CCQ25671.1,
CBX25213.1,
CCQ25672.1,
CBX25214.1,
CAA93427.2
Gene_ORFName:
ZK593.5,
CELE_ZK593.5,
ZK593.5,
CELE_ZK593.5,
ZK593.5,
CELE_ZK593.5,
CELE_ZK593.5,
ZK593.5,
ZK593.5,
CELE_ZK593.5
|
| Protein sequencees |
RefSeq:
NP_001263781.1,
NP_001263782.1,
NP_001255521.1,
NP_001255522.1,
NP_001369908.1
|
| Others |
UniRef100:
UniRef100_L8EC32,
UniRef100_Q23542,
UniRef100_E2JKZ0,
UniRef100_L8E938
UniRef90:
UniRef90_E2JKZ0
UniRef50:
UniRef50_E2JKZ0
UniGene:
Cel.5191
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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