Type | Description |
---|---|
Definition | NAD-dependent protein deacetylase sir-2.1 |
Date | Results | Publications |
---|---|---|
2019-03-02 10:47:00 | metazoan SIRT1 orthologs as Hsp90 clients and reveal a novel crosstalk between the proteostasis and nutrient signaling networks, which may have implications in various age related diseases. | 30463299 |
2016-05-21 10:11:00 | SIRT1 plays essential roles in cell survival, inflammation, energy metabolism, and aging. | 25976661 |
2016-02-13 11:08:00 | The authors show that the mating circuits' functional durability depends on the metabolic regulator SIR-2.1, a NAD(+)-dependent histone deacetylase. | 24755287 |
2015-07-25 11:40:00 | Sir-2.1; dnj-14 double mutants showed full lifespan rescue by resveratrol. | 24947438 |
2014-12-20 12:05:00 | Prolongation of survival under glucose exposure by quercetin is dependent on SIR-2.1, DAF-12, and MDT-15 | 24407905 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
SIR2_CAEEL,
D3YT50_CAEEL
UniprotKB:
Q21921,
D3YT50
UniParc:
UPI0001CDEBA7,
UPI0000078F39
EMBL:
Z70310,
BX284604
EnsemblGenome:
WBGene00004800
KO:
cel:CELE_R11A8.4
|
Nucleutide sequences |
EMBL-CDS:
CAA94364.1,
CBK19468.1
Gene_ORFName:
R11A8.4,
CELE_R11A8.4,
R11A8.4
EnsemblGenome_TRS:
R11A8.4a.1,
R11A8.4a.2
|
Protein sequencees |
EnsemblGenome_PRO:
R11A8.4a.2,
R11A8.4a.1
RefSeq:
NP_001255485.1,
NP_001255484.1
|
Others |
UniRef100:
UniRef100_Q21921
UniRef90:
UniRef90_Q21921
UniRef50:
UniRef50_Q21921
UniGene:
Cel.12479
|