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177924 sir-2.1

177924

sir-2.1

NAD-dependent protein deacetylase sir-2.1

protein-coding

Caenorhabditis elegans

基因描述

Type Description
Definition NAD-dependent protein deacetylase sir-2.1

研究结论

Date Results Publications
2019-03-02 10:47:00 metazoan SIRT1 orthologs as Hsp90 clients and reveal a novel crosstalk between the proteostasis and nutrient signaling networks, which may have implications in various age related diseases. 30463299
2016-05-21 10:11:00 SIRT1 plays essential roles in cell survival, inflammation, energy metabolism, and aging. 25976661
2016-02-13 11:08:00 The authors show that the mating circuits' functional durability depends on the metabolic regulator SIR-2.1, a NAD(+)-dependent histone deacetylase. 24755287
2015-07-25 11:40:00 Sir-2.1; dnj-14 double mutants showed full lifespan rescue by resveratrol. 24947438
2014-12-20 12:05:00 Prolongation of survival under glucose exposure by quercetin is dependent on SIR-2.1, DAF-12, and MDT-15 24407905

名称对应

Type IDs
Gene
UniProtKB-ID: SIR2_CAEEL, D3YT50_CAEEL
UniprotKB: Q21921, D3YT50
UniParc: UPI0001CDEBA7, UPI0000078F39
EMBL: Z70310, BX284604
EnsemblGenome: WBGene00004800
KO: cel:CELE_R11A8.4
Nucleutide sequences
EMBL-CDS: CAA94364.1, CBK19468.1
Gene_ORFName: R11A8.4, CELE_R11A8.4, R11A8.4
EnsemblGenome_TRS: R11A8.4a.1, R11A8.4a.2
Protein sequencees
EnsemblGenome_PRO: R11A8.4a.2, R11A8.4a.1
RefSeq: NP_001255485.1, NP_001255484.1
Others
UniRef100: UniRef100_Q21921
UniRef90: UniRef90_Q21921
UniRef50: UniRef50_Q21921
UniGene: Cel.12479

全选

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