| Type | Description |
|---|---|
| Definition | dynein cytoplasmic 1 heavy chain 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:15:00 | Acting like a sponge of miR-140-5p, silenced circDYNC1H1 downregulated SULT2B1 to restrain HCC cell proliferation. | 30864145 |
| 2020-02-22 11:53:00 | Significantly decreased methylation of CpG islands within exon 37 of the DYNC1H1 gene was observed in patients with a severe SMA manifestation (type I) compared to mildly affected SMA patients (types III-IV). | 30246859 |
| 2019-05-25 11:47:00 | Over the years other phenotypes including Charcot Marie Tooth type 2 and hereditary mental retardation with cortical neural migration defects have also been reported to be caused by DYNC1H1 mutations | 29306600 |
| 2019-01-12 10:19:00 | Using in vitro total internal reflection fluorescence microscopy, the study observed that higher concentrations of Ndc80 inhibited dynein binding to microtubules, providing evidence that Ndc80 and dynein antagonize each other's function. | 29475948 |
| 2018-09-01 10:54:00 | Taken together, these results demonstrate DYNC1H1 as a strong candidate and RTP1 as a potential candidate on the onset of epileptic encephalopathies. | 28325891 |
| Type | IDs |
|---|---|
| Synonymous | CMT2O, DHC1, DHC1a, DNCH1, DNCL, DNECL, DYHC, Dnchc1, HL-3, SMALED1, p22 |
| Gene |
UniProtKB-ID:
DYHC1_HUMAN
UniprotKB:
Q14204
UniParc:
UPI00001B515A
EMBL:
U53530,
AB290157,
BC021297,
AY682080,
L23958,
AB002323
Ensembl:
ENSG00000197102
KO:
hsa:1778
|
| Nucleutide sequences |
EMBL-CDS:
AAA16065.1,
AAB09727.1,
BAA20783.3,
AAT74625.1,
BAG06711.1,
AAH21297.2
Ensembl_TRS:
ENST00000360184
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348965
RefSeq:
NP_001367.2
|
| Others |
UniRef100:
UniRef100_Q14204
UniRef90:
UniRef90_Q14204
UniRef50:
UniRef50_Q14204
UniGene:
Hs.614080
CCDS:
CCDS9966.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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