| Type | Description |
|---|---|
| Definition | methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase |
| Date | Results | Publications |
|---|---|---|
| 2017-10-07 12:51:00 | Data suggest that Ad4BP plays role in regulation of intracellular NADPH concentration via transcription of Me1 and Mthfd2 genes in adrenocortical cells. (Ad4BP = nuclear receptor subfamily 5 group A member 1; Me1 = malic enzyme 1; Mthfd2 = bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase) | 28202838 |
| 2010-01-21 00:00:00 | Mammalian mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase derived from a trifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase. | 12061812 |
| 2010-01-21 00:00:00 | Results describe the ubiquitous expression of NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase in mouse embryos, suggesting it has a broad role during embryogenesis. | 15342116 |
| 2010-01-21 00:00:00 | A mutation in methylenetetrahydrofolate reductase (MTHFR) gene, may contribute to the risk of both arterial and deep-vein thrombosis in patients with nephrotic syndrome. | 18030499 |
| 2010-01-21 00:00:00 | results demonstrate a metabolic role for NAD+ dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase in supporting purine biosynthesis | 12646567 |
| Type | IDs |
|---|---|
| Synonymous | AW558851, NMDMC |
| Gene |
UniProtKB-ID:
MTDC_MOUSE
UniprotKB:
P18155
UniParc:
UPI0000001987
EMBL:
BC019511,
M63441,
M63440,
J04627,
M63415,
AK159680,
AK076019,
M63444,
M63443,
S52980,
AK165840,
M63445,
M63442,
M63439
Ensembl:
ENSMUSG00000005667
KO:
mmu:17768
|
| Nucleutide sequences |
EMBL-CDS:
BAE35283.1,
AAA39827.1,
BAC36124.1,
AAH19511.1,
AAA39828.1,
BAE38407.1
Ensembl_TRS:
ENSMUST00000005810
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005810
RefSeq:
NP_032664.1,
XP_006505760.1,
XP_011239547.1
|
| Others |
UniRef100:
UniRef100_P18155
UniRef90:
UniRef90_P18155
UniRef50:
UniRef50_P18155
UniGene:
Mm.443,
Mm.475021
CCDS:
CCDS20277.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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